Resorufin methyl ether (7-Meth)oxyresorufin), Fluorometric cytochrome P450 substrate (ab145372)

Overview

  • Product name

    Resorufin methyl ether (7-Meth)oxyresorufin), Fluorometric cytochrome P450 substrate
  • Description

    Fluorometric cytochrome P450 substrate
  • Alternative names

    • 7-Methoxyresorufin
  • Biological description

    Fluorometric competitive cytochrome P450 substrate. Resorufin (ab145435) butyrate analog. Shows selectivity for CYP1A (Ki = 20 μM, dealkylation 0.5 μM substrate).
  • Purity

    > 98%
  • CAS Number

    5725-89-3
  • Chemical structure

    Chemical Structure

Properties

  • Excitation

    571nm
  • Emission

    571nm
  • Chemical name

    7-Methoxyphenoxazin-3-one
  • Molecular weight

    227.22
  • Molecular formula

    C13H9NO3
  • PubChem identifier

    119220
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol and in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    COC1=CC2=C(C=C1)N=C3C=CC(=O)C=C3O2
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Welch ME  et al. Generalized platform for antibody detection using the antibody catalyzed water oxidation pathway. J Am Chem Soc 136:1879-83 (2014). Read more (PubMed: 24410628) »
  • McCart C & Ffrench-Constant RH Dissecting the insecticide-resistance- associated cytochrome P450 gene Cyp6g1. Pest Manag Sci 64:639-45 (2008). Read more (PubMed: 18338338) »
  • Kim D & Guengerich FP Enhancement of 7-methoxyresorufin O-demethylation activity of human cytochrome P450 1A2 by molecular breeding. Arch Biochem Biophys 432:102-8 (2004). Read more (PubMed: 15519301) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab145372.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up