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Protocols and troubleshooting
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Research tools to study tau in neuroinflammation and Alzheimer's disease. Detect total tau, phospho tau and explore tau aggregation inhibitors.
Watch this webinar presented by Dr Akihiko Takashima and Dr Ioannis Sotiropoulos to learn the emerging views on the role and function of Tau in neurons (from soma to synapse), including its recently-suggested contributions to scaffolding and signaling.
Read about how posttranslational modification and mislocalization of the tau protein contributes to Alzheimer's disease.
Get to the root of Alzheimer's disease with this poster depicting the interactions between beta amyloid (Aß), tau, astrocytes and microglia.
An interactive pathway on Alzheimer's disease highlighting the mechanisms of amyloid plaque and neurofibrillary tangle formation from APP and tau.
Read an overview of GSK3 functions in the insulin, Wnt, Reelin & Hedgehog signaling pathways as well as in neurodegenerative & neurological diseases.
Listen in as Dr Lizzie Glennon, Ph.D, discusses how disruption of axonal transport contributes to the development of Alzheimer's disease, and why this makes it a good potential target for drug discovery.
Get to the root cause of neurodegeneration with a comprehensive range of neuroinflammation research tools to detect glia, aggregated proteins and proinflammatory mediators in Alzheimer's and Parkinson's diseases.
Complete guide to selecting microtubule inhibitors, tubulin inhibitors and microtubule-associating protein (MAP) targeting compounds.
Read all about the first day of Crossing boundaries: linking metabolism to epigenetics, Cambridge, MA. A detailed report written by Heather Allan.