Key features and details
- Mouse monoclonal [2F7] to Respiratory Syncytial Virus
- Suitable for: WB, IHC-Fr, ICC/IF, ELISA
- Reacts with: Respiratory syncytial virus
- Isotype: IgG1
Product nameAnti-Respiratory Syncytial Virus antibody [2F7]
See all Respiratory Syncytial Virus primary antibodies
DescriptionMouse monoclonal [2F7] to Respiratory Syncytial Virus
Tested applicationsSuitable for: WB, IHC-Fr, ICC/IF, ELISAmore details
Species reactivityReacts with: Respiratory syncytial virus
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferConstituents: 0.75% Glycine, 1.21% Tris, 2% Sucrose
Concentration information loading...
PurityProtein A purified
Light chain typekappa
Our Abpromise guarantee covers the use of ab43812 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/5000. Predicted molecular weight: 48 , 70 kDa.|
|IHC-Fr||1/100 - 1/500.|
|ICC/IF||1/100 - 1/500.
Immunocytology on infected cells.
|ELISA||1/2000 - 1/1000.|
RelevanceRespiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells.
Cellular localizationVirion. Host cytoplasm
- Entrez Gene: 2829063 Respiratory syncytial virus
- RS virus antibody
- RSV antibody
ab43812 has been referenced in 12 publications.
- Mehedi M et al. Multicolor Stimulated Emission Depletion (STED) Microscopy to Generate High-resolution Images of Respiratory Syncytial Virus Particles and Infected Cells. Bio Protoc 7:N/A (2017). PubMed: 29057295
- Liang B et al. Improved Prefusion Stability, Optimized Codon Usage, and Augmented Virion Packaging Enhance the Immunogenicity of Respiratory Syncytial Virus Fusion Protein in a Vectored-Vaccine Candidate. J Virol 91:N/A (2017). PubMed: 28539444
- Coates M et al. Preclinical Characterization of PC786, an Inhaled Small-Molecule Respiratory Syncytial Virus L Protein Polymerase Inhibitor. Antimicrob Agents Chemother 61:N/A (2017). PubMed: 28652242
- Mehedi M et al. A novel host factor for human respiratory syncytial virus. Commun Integr Biol 10:e1319025 (2017). ICC/IF ; Human . PubMed: 28702128
- Mehedi M et al. Actin-Related Protein 2 (ARP2) and Virus-Induced Filopodia Facilitate Human Respiratory Syncytial Virus Spread. PLoS Pathog 12:e1006062 (2016). PubMed: 27926942