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  1. Link

    respiratory-syncytial-virus-antibody-ab20745.pdf

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Microbiology Organism Virus RNA Virus single stranded RNA negative strand virus Resp. Syncytial Virus
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Anti-Respiratory Syncytial Virus antibody (ab20745)

  • Datasheet
  • SDS
Submit a review Q&A (1)References (28)

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Key features and details

  • Goat polyclonal to Respiratory Syncytial Virus
  • Suitable for: Conjugation, ICC/IF, IHC-P, WB, ELISA
  • Reacts with: Respiratory syncytial virus
  • Isotype: IgG

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Overview

  • Product name

    Anti-Respiratory Syncytial Virus antibody
    See all Respiratory Syncytial Virus primary antibodies
  • Description

    Goat polyclonal to Respiratory Syncytial Virus
  • Host species

    Goat
  • Tested applications

    Suitable for: Conjugation, ICC/IF, IHC-P, WB, ELISAmore details
  • Species reactivity

    Reacts with: Respiratory syncytial virus
  • Immunogen

    Tissue, cells or virus corresponding to Respiratory Syncytial Virus. Viral lysate of Human RSV isolate.

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituent: 0.0268% PBS
  • Concentration information loading...
  • Purity

    IgG fraction
  • Purification notes

    Sodium sulphate precipitation and DEAE chromatography.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Microbiology
    • Organism
    • Virus
    • RNA Virus
    • single stranded RNA negative strand virus
    • Resp. Syncytial Virus

Associated products

  • Compatible Secondaries

    • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
    • Donkey Anti-Goat IgG H&L (HRP) (ab205723)
  • Isotype control

    • Goat IgG, polyclonal - Isotype Control (ab37373)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab20745 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Conjugation
Use at an assay dependent concentration.
ICC/IF
Use at an assay dependent concentration. PubMed: 20647383
IHC-P
Use at an assay dependent concentration.
WB
Use at an assay dependent concentration.
ELISA
Use at an assay dependent concentration.
Notes
Conjugation
Use at an assay dependent concentration.
ICC/IF
Use at an assay dependent concentration. PubMed: 20647383
IHC-P
Use at an assay dependent concentration.
WB
Use at an assay dependent concentration.
ELISA
Use at an assay dependent concentration.

Target

  • Relevance

    Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells.
  • Cellular localization

    Virion. Host cytoplasm
  • Database links

    • Entrez Gene: 2829063 Respiratory syncytial virus
    • Alternative names

      • RS virus antibody
      • RSV antibody

    Protocols

    • Immunohistochemistry protocols
    • Immunocytochemistry & immunofluorescence protocols
    • Western blot protocols

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (28)

    Publishing research using ab20745? Please let us know so that we can cite the reference in this datasheet.

    ab20745 has been referenced in 28 publications.

    • Pearson H  et al. TMEM16A/ANO1 calcium-activated chloride channel as a novel target for the treatment of human respiratory syncytial virus infection. Thorax 76:64-72 (2021). PubMed: 33109690
    • de Souza Cardoso R  et al. Human Respiratory Syncytial Virus Infection in a Human T Cell Line Is Hampered at Multiple Steps. Viruses 13:N/A (2021). PubMed: 33540662
    • Braun MR  et al. Respiratory syncytial virus M2-1 protein associates non-specifically with viral messenger RNA and with specific cellular messenger RNA transcripts. PLoS Pathog 17:e1009589 (2021). PubMed: 34003848
    • Touzelet O  et al. The Secretome Profiling of a Pediatric Airway Epithelium Infected with hRSV Identified Aberrant Apical/Basolateral Trafficking and Novel Immune Modulating (CXCL6, CXCL16, CSF3) and Antiviral (CEACAM1) Proteins. Mol Cell Proteomics 19:793-807 (2020). PubMed: 32075873
    • Blanchard EL  et al. Polymerase-tagged respiratory syncytial virus reveals a dynamic rearrangement of the ribonucleocapsid complex during infection. PLoS Pathog 16:e1008987 (2020). PubMed: 33031461
    View all Publications for this product

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    Question

    What beads are recommended for IP with ab20795?

    Read More

    Abcam community

    Verified customer

    Asked on Mar 05 2009

    Answer

    Thank you for your enquiry. According to our laboratory notes we would recommend a ProteinG beads system for immunoprecipitation of goat antibodies. I hope this information helps. Please do not hesitate to contact us if you need any more advice or information.

    Read More

    Abcam Scientific Support

    Answered on Mar 05 2009

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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