Anti-Respiratory Syncytial Virus antibody (ab20745)
Key features and details
- Goat polyclonal to Respiratory Syncytial Virus
- Suitable for: Conjugation, ICC/IF, IHC-P, WB, ELISA
- Reacts with: Respiratory syncytial virus
- Isotype: IgG
Overview
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Product name
Anti-Respiratory Syncytial Virus antibody
See all Respiratory Syncytial Virus primary antibodies -
Description
Goat polyclonal to Respiratory Syncytial Virus -
Host species
Goat -
Tested applications
Suitable for: Conjugation, ICC/IF, IHC-P, WB, ELISAmore details -
Species reactivity
Reacts with: Respiratory syncytial virus -
Immunogen
Tissue, cells or virus corresponding to Respiratory Syncytial Virus. Viral lysate of Human RSV isolate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 0.0268% PBS -
Concentration information loading... -
Purity
IgG fraction -
Purification notes
Sodium sulphate precipitation and DEAE chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab20745 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Conjugation |
Use at an assay dependent concentration.
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| ICC/IF |
Use at an assay dependent concentration. PubMed: 20647383
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| IHC-P |
Use at an assay dependent concentration.
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| WB |
Use at an assay dependent concentration.
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| ELISA |
Use at an assay dependent concentration.
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| Notes |
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Conjugation
Use at an assay dependent concentration. |
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ICC/IF
Use at an assay dependent concentration. PubMed: 20647383 |
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IHC-P
Use at an assay dependent concentration. |
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WB
Use at an assay dependent concentration. |
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ELISA
Use at an assay dependent concentration. |
Target
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Relevance
Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells. -
Cellular localization
Virion. Host cytoplasm -
Database links
- Entrez Gene: 2829063 Respiratory syncytial virus
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Alternative names
- RS virus antibody
- RSV antibody
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (28)
ab20745 has been referenced in 28 publications.
- Pearson H et al. TMEM16A/ANO1 calcium-activated chloride channel as a novel target for the treatment of human respiratory syncytial virus infection. Thorax 76:64-72 (2021). PubMed: 33109690
- de Souza Cardoso R et al. Human Respiratory Syncytial Virus Infection in a Human T Cell Line Is Hampered at Multiple Steps. Viruses 13:N/A (2021). PubMed: 33540662
- Braun MR et al. Respiratory syncytial virus M2-1 protein associates non-specifically with viral messenger RNA and with specific cellular messenger RNA transcripts. PLoS Pathog 17:e1009589 (2021). PubMed: 34003848
- Touzelet O et al. The Secretome Profiling of a Pediatric Airway Epithelium Infected with hRSV Identified Aberrant Apical/Basolateral Trafficking and Novel Immune Modulating (CXCL6, CXCL16, CSF3) and Antiviral (CEACAM1) Proteins. Mol Cell Proteomics 19:793-807 (2020). PubMed: 32075873
- Blanchard EL et al. Polymerase-tagged respiratory syncytial virus reveals a dynamic rearrangement of the ribonucleocapsid complex during infection. PLoS Pathog 16:e1008987 (2020). PubMed: 33031461