Anti-Respiratory Syncytial Virus antibody (ab20745)

Submit a review Q&A (1)References (24)

Key features and details

  • Goat polyclonal to Respiratory Syncytial Virus
  • Suitable for: IHC-P, WB, ELISA
  • Reacts with: Respiratory syncytial virus
  • Isotype: IgG

Overview

  • Product name

    Anti-Respiratory Syncytial Virus antibody
    See all Respiratory Syncytial Virus primary antibodies

  • Description

    Goat polyclonal to Respiratory Syncytial Virus

  • Host species

    Goat

  • Tested applications

    Suitable for: IHC-P, WB, ELISAmore details

  • Species reactivity

    Reacts with: Respiratory syncytial virus

  • Immunogen

    Tissue, cells or virus corresponding to Respiratory Syncytial Virus. Viral lysate of Human RSV isolate.

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituent: 0.0268% PBS
  • Concentration information loading...

  • Purity

    IgG fraction

  • Purification notes

    Sodium sulphate precipitation and DEAE chromatography.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Research areas

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab20745 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
Use at an assay dependent concentration.
WB
Use at an assay dependent concentration.
ELISA
Use at an assay dependent concentration.
Notes
IHC-P
Use at an assay dependent concentration.
WB
Use at an assay dependent concentration.
ELISA
Use at an assay dependent concentration.

Target

  • Relevance

    Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells.

  • Cellular localization

    Virion. Host cytoplasm

  • Database links

    • Alternative names

      • RS virus antibody
      • RSV antibody

    References (24)

    Publishing research using ab20745? Please let us know so that we can cite the reference in this datasheet.

    ab20745 has been referenced in 24 publications.

    • Pearson H  et al. TMEM16A/ANO1 calcium-activated chloride channel as a novel target for the treatment of human respiratory syncytial virus infection. Thorax 76:64-72 (2021). PubMed: 33109690
    • Touzelet O  et al. The Secretome Profiling of a Pediatric Airway Epithelium Infected with hRSV Identified Aberrant Apical/Basolateral Trafficking and Novel Immune Modulating (CXCL6, CXCL16, CSF3) and Antiviral (CEACAM1) Proteins. Mol Cell Proteomics 19:793-807 (2020). PubMed: 32075873
    • Ko SH  et al. Interference of DNAJB6/MRJ Isoform Switch by Morpholino Inhibits Replication of HIV-1 and RSV. Mol Ther Nucleic Acids 14:251-261 (2019). PubMed: 30641477
    • Hu M  et al. Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production. Elife 8:N/A (2019). PubMed: 31246170
    • Ezzat K  et al. The viral protein corona directs viral pathogenesis and amyloid aggregation. Nat Commun 10:2331 (2019). PubMed: 31133680
    View all Publications for this product

    Customer reviews and Q&As

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    Question

    What beads are recommended for IP with ab20795?

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    Answer

    Thank you for your enquiry. According to our laboratory notes we would recommend a ProteinG beads system for immunoprecipitation of goat antibodies. I hope this information helps. Please do not hesitate to contact us if you need any more advice or information.

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