Product nameAnti-Respiratory Syncytial Virus antibody (FITC)
See all Respiratory Syncytial Virus primary antibodies
DescriptionGoat polyclonal to Respiratory Syncytial Virus (FITC)
ConjugationFITC. Ex: 493nm, Em: 528nm
Tested applicationsSuitable for: ICC/IF, ELISA, IHC-Pmore details
Species reactivityDoes not react with Para 1-3, Influenza A & B or Adenovirus by IFA. Reacts well with bovine isolates. Negative against HEp-2 cells and WI-38 cells. Not yet tested in other species.
Human RSV isolate
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.20
Preservative: 0.1% Sodium azide
Constituents: 0.0268% PBS, 1% BSA
Concentration information loading...
Our Abpromise guarantee covers the use of ab20391 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use at an assay dependent concentration. PubMed: 20647383|
|ELISA||Use at an assay dependent concentration.|
|IHC-P||1/10 - 1/50.|
RelevanceRespiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells.
Cellular localizationVirion. Host cytoplasm
- RS virus antibody
- RSV antibody
This product has been referenced in:
- Aljabr W et al. Investigating the Influence of Ribavirin on Human Respiratory Syncytial Virus RNA Synthesis by Using a High-Resolution Transcriptome Sequencing Approach. J Virol 90:4876-88 (2016). IF . Read more (PubMed: 26656699) »
- Smith CM et al. Respiratory syncytial virus increases the virulence of Streptococcus pneumoniae by binding to penicillin binding protein 1a. A new paradigm in respiratory infection. Am J Respir Crit Care Med 190:196-207 (2014). Read more (PubMed: 24941423) »