Anti-Respiratory Syncytial Virus fusion protein antibody [RSV3216 (B016)] (ab24011)
Key features and details
- Mouse monoclonal [RSV3216 (B016)] to Respiratory Syncytial Virus fusion protein
- Suitable for: Flow Cyt, WB, IP, ICC/IF, Electron Microscopy, Sandwich ELISA
- Reacts with: Respiratory syncytial virus
- Isotype: IgG2b
Overview
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Product name
Anti-Respiratory Syncytial Virus fusion protein antibody [RSV3216 (B016)] -
Description
Mouse monoclonal [RSV3216 (B016)] to Respiratory Syncytial Virus fusion protein -
Host species
Mouse -
Specificity
Recognises a Respiratory Syncytial Virus fusion protein (46kD and 22kD s-s linked glycoprotein). -
Tested applications
Suitable for: Flow Cyt, WB, IP, ICC/IF, Electron Microscopy, Sandwich ELISAmore details -
Species reactivity
Reacts with: Respiratory syncytial virus -
Immunogen
Tissue, cells or virus corresponding to Respiratory Syncytial Virus fusion protein. Bovine RSV strains: 127, SNK and 9007. Human RSV strains: Long, Randall, 8/60, and A/2.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.50
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
RSV3216 (B016) -
Myeloma
NS1 -
Isotype
IgG2b -
Research areas
Associated products
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Compatible Secondaries
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Conjugation kits
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Isotype control
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sELISA pair antibody
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab24011 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt | (1) |
Use at an assay dependent concentration.
ab170192 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
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| WB |
Use at an assay dependent concentration.
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| IP |
Use at an assay dependent concentration.
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| ICC/IF |
Use at an assay dependent concentration.
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| Electron Microscopy |
Use at an assay dependent concentration.
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| Sandwich ELISA |
Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Mouse monoclonal [B023] to Respiratory Syncytial Virus Nucleoprotein (ab22501). Use ab34992 as capture antibody
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| Notes |
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Flow Cyt
Use at an assay dependent concentration. ab170192 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
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WB
Use at an assay dependent concentration. |
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IP
Use at an assay dependent concentration. |
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ICC/IF
Use at an assay dependent concentration. |
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Electron Microscopy
Use at an assay dependent concentration. |
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Sandwich ELISA
Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Mouse monoclonal [B023] to Respiratory Syncytial Virus Nucleoprotein (ab22501). Use ab34992 as capture antibody |
Target
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Relevance
Respiratory Syncytial Virus fusion protein directs fusion of viral and cellular membranes, resulting in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia. -
Cellular localization
Cell Membrane -
Database links
- Entrez Gene: 1494475 Respiratory syncytial virus
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Alternative names
- Fusion glycoprotein F0 antibody
- Fusion glycoprotein F1 antibody
- Fusion glycoprotein F2 antibody
see all
Protocols
Datasheets and documents
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Datasheet download
References (4)
ab24011 has been referenced in 4 publications.
- Du X et al. Respiratory syncytial virus infection-induced mucus secretion by down-regulation of miR-34b/c-5p expression in airway epithelial cells. J Cell Mol Med 24:12694-12705 (2020). PubMed: 32939938
- Hu T et al. TLR4 and nucleolin influence cell injury, apoptosis and inflammatory factor expression in respiratory syncytial virus-infected N2a neuronal cells. J Cell Biochem 120:16206-16218 (2019). PubMed: 31081244
- Yuan X et al. Respiratory syncytial virus prolifically infects N2a neuronal cells, leading to TLR4 and nucleolin protein modulations and RSV F protein co-localization with TLR4 and nucleolin. J Biomed Sci 25:13 (2018). Mouse . PubMed: 29427996
- Jans J et al. Actin- and clathrin-dependent mechanisms regulate interferon gamma release after stimulation of human immune cells with respiratory syncytial virus. Virol J 13:52 (2016). PubMed: 27004689
