Overview

  • Product name
    Reticulol, Topoisomerase I inhibitor
  • Description
    Topoisomerase I inhibitor. Antiproliferative agent.
  • Biological description
    Topoisomerase I inhibitor. Antiproliferative agent. Inhibits cyclic adenosine 3', 5'-monophosphate phosphodiesterase. Shows necrotic effects against cancer cells. Inhibits metastasis. Shows antitumor effects in vivo.
  • Purity
    > 98%
  • CAS Number
    26246-41-3
  • Chemical structure
    Chemical Structure

Properties

References

This product has been referenced in:
  • Lim DS  et al. Antitumor efficacy of reticulol from Streptoverticillium against the lung metastasis model B16F10 melanoma. Lung metastasis inhibition by growth inhibition of melanoma. Chemotherapy 49:146-53 (2003). Read more (PubMed: 12815208) »
  • Lim DS  et al. Topoisomerase I inactivation by reticulol and its in vivo cytotoxicity against B16F10 melanoma. Chemotherapy 49:257-63 (2003). Read more (PubMed: 14504438) »
  • Furutani Y  et al. Reticulol, an inhibitor of cyclic adenosine 3', 5'-monophosphate phosphodiesterase. J Antibiot (Tokyo) 28:558-60 (1975). Read more (PubMed: 168174) »

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