Key features and details
- Mouse monoclonal [S128] to Retinal S antigen
- Suitable for: WB, IHC-Fr
- Reacts with: Cow, Pig
- Isotype: IgG1
Product nameAnti-Retinal S antigen antibody [S128]
See all Retinal S antigen primary antibodies
DescriptionMouse monoclonal [S128] to Retinal S antigen
Tested applicationsSuitable for: WB, IHC-Frmore details
Species reactivityReacts with: Cow, Pig
Predicted to work with: Mouse, Rat, Human
Recombinant fragment corresponding to Cow Retinal S antigen. (With the first 20 amino acids of the C-terminus truncated).
Database link: P08168
- WB: Bovine retinal extract. ICC/IF: Pig retina tissue.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.07% Sodium azide
Constituents: PBS, 50% Glycerol
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab190315 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/5000. Detects a band of approximately 48 kDa (predicted molecular weight: 45 kDa).|
|IHC-Fr||Use at an assay dependent concentration.|
FunctionArrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase.
Tissue specificityRetina and pineal gland.
Involvement in diseaseDefects in SAG are a cause of congenital stationary night blindness Oguchi type 1 (CSNBO1) [MIM:258100]; also known as Oguchi disease. Congenital stationary night blindness is a non-progressive retinal disorder characterized by impaired night vision. CSNBO is an autosomal recessive form associated with fundus discoloration and abnormally slow dark adaptation.
Sequence similaritiesBelongs to the arrestin family.
- Information by UniProt
- 48 kDa protein antibody
- Arrestin 1 antibody
- Arrestin antibody
Anti-Retinal S antigen antibody [S128] (ab190315) at 1/5000 dilution + Bovine retinal extract
Predicted band size: 45 kDa
Observed band size: 48 kDa why is the actual band size different from the predicted?
Confocal analysis of pig retina labeling Retinal S antigen with ab190315 at 1/1000 dilution (green). The red stain is Fox2, an RNA binding nuclear protein related to Fox3/NeuN, which stains nuclei of horizontal neurons and some other neurons in the INL and IPL. Nuclear DNA was revealed with DAPI (blue).
ab190315 has not yet been referenced specifically in any publications.