Product nameAnti-Retinoic Acid Receptor beta antibody
See all Retinoic Acid Receptor beta primary antibodies
DescriptionRabbit polyclonal to Retinoic Acid Receptor beta
SpecificityThis antibody shows slight cross-reactivity to RAR alpha but does not detect RAR gamma.
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Human, Saccharomyces cerevisiae
- SH-SY5Y cell extract.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.05% Sodium azide
Constituent: 99% PBS
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Retinoic & Retinoid
Immunizing Peptide (Blocking)
Our Abpromise guarantee covers the use of ab5792 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Detects a band of approximately 52 kDa (predicted molecular weight: 53 kDa).Can be blocked with Retinoic Acid Receptor beta peptide (ab5897).|
FunctionReceptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
Involvement in diseaseMicrophthalmia, syndromic, 12
Sequence similaritiesBelongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain.
DomainComposed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
Cellular localizationCytoplasm and Nucleus.
- Information by UniProt
- HAP antibody
- HBV-activated protein antibody
- NR1B2 antibody
All lanes : Anti-Retinoic Acid Receptor beta antibody (ab5792) at 1/1000 dilution
Lane 1 : SH-SY5Y cell lysate
Lane 2 : HepG2 cell lysate
Lane 3 : Mouse heart cell lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 53 kDa
Observed band size: 58 kDa why is the actual band size different from the predicted?
ab5792 has not yet been referenced specifically in any publications.