Overview

  • Product name

    Reveromycin A, G1 phase cell cycle inhibitor
  • Description

    G1 phase cell cycle inhibitor and selective protein synthesis inhibitor
  • Biological description

    G1 phase cell cycle inhibitor and selective protein synthesis inhibitor. Induces apoptosis in vitro. Inhibits eukaryotic cell growth. Antitumor, antifungal and bone resorption agent. Active in vitro and in vivo.
  • Purity

    > 98%
  • CAS Number

    134615-37-5
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Woo JT  et al. Reveromycin A, an agent for osteoporosis, inhibits bone resorption by inducing apoptosis specifically in osteoclasts. Proc Natl Acad Sci U S A 103:4729-34 (2006). Read more (PubMed: 16537392) »
  • Miyamoto Y  et al. Identification of Saccharomyces cerevisiae isoleucyl-tRNA synthetase as a target of the G1-specific inhibitor Reveromycin A. J Biol Chem 277:28810-4 (2002). Read more (PubMed: 12050165) »
  • Takahashi H  et al. Reveromycins, new inhibitors of eukaryotic cell growth. II. Biological activities. J Antibiot (Tokyo) 45:1414-9 (1992). Read more (PubMed: 1429226) »

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