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Rabbit polyclonal to Rffl
Predicted to work with:
Mouse, Rat, Cow, Dog
Recombinant full length protein, corresponding to amino acids 1-363 of Human Rffl.
Human Brain, Cortex tissue.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.01% Sodium azide Constituents: 0.88% Sodium chloride, 0.27% Potassium phosphate
Concentration information loading...
Protein A purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 41 kDa.
1/4000 - 1/20000.
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Use at an assay dependent concentration.
Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates.
Ubiquitous. Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes.
Protein modification; protein ubiquitination.
Contains 1 FYVE-type zinc finger.
Contains 1 RING-type zinc finger. Contains 2 SAP domains.
Rapidly degraded after stimulation with TNFSF10, probably by caspases.
Auto-ubiquitinated (in vitro). Palmitoylated.
Information by UniProt
Caspase regulator CARP2 antibody
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Rffl antibody (ab115452)
ab115452, at 5µg/ml, staining Rffl in Formalin-fixed, Paraffin-embedded Human Brain cortex tissue by Immunohistochemistry followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"