Key features and details
- Rabbit polyclonal to RG1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-RG1 antibody
DescriptionRabbit polyclonal to RG1
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Recombinant fragment corresponding to Human RG1 aa 900-1080.
SAFNSDTNRAPQNSSPFSKHHTEISVSTNEQAIAVENAVTTMASQPISTK SENICNSTREIQGIEKHPYPESKPEEVSRSSGIVTSGSRKERCIGQIFQT EEYSVEKSLGPMILINKPLENMEEARHENEGLVSSGQSLYTSGEKESDSS ASTSLPVEESQAQGNESLFSKYTNSKIPYFL
Database link: Q16821
- IHC-P: Human skeletal muscle and heart tissue.
Previously labelled as PPP1R3A.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab230285 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/20 - 1/200.|
FunctionSeems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase.
Tissue specificitySkeletal muscle and heart.
Involvement in diseaseDiabetes mellitus, non-insulin-dependent
Sequence similaritiesContains 1 CBM21 (carbohydrate binding type-21) domain.
DomainThe CBM21 domain is known to be involved in the localization to glycogen and is characteristic of some regulatory subunit of phosphatase complexes.
modificationsPhosphorylation at Ser-46 by ISPK stimulates the dephosphorylation of glycogen synthase and phosphorylase kinase.
- Information by UniProt
- Glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle antibody
- Glycogen associated regulatory subunit of protein phosphatase 1 antibody
- GM antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab230285 has not yet been referenced specifically in any publications.