Anti-RGPD5 antibody (ab106360)
Key features and details
- Rabbit polyclonal to RGPD5
- Suitable for: ICC/IF, IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-RGPD5 antibody -
Description
Rabbit polyclonal to RGPD5 -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IF, IHC-P, WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
A 13 amino acid peptide from near the N terminus of Human RGPD5 (NP_005045).
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Positive control
- Human Thymus Tissue Lysate, Human testis tissue
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
Affinity chromatography purified via peptide column -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab106360 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ICC/IF |
Use a concentration of 20 µg/ml.
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IHC-P |
Use a concentration of 10 µg/ml.
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 199 kDa.
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Notes |
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ICC/IF
Use a concentration of 20 µg/ml. |
IHC-P
Use a concentration of 10 µg/ml. |
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 199 kDa. |
Target
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Relevance
The RANBP2-like and GRIP domain containing 5 protein (RGPD5) has high similarity to RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. The gene coding for RGPD5 is thought to have arisen from a gene duplication event of RANBP2 as these highly homologous genes are located close to each other at chromosome 2q11-q12. RGPD5 was identified as an HIV dependency factor (HDF), suggesting that RGPD5 may be an important drug target in HIV treatment. At least two isoforms of RGPD5 are known to exist, of which the shorter isoform is expressed primarily in testis, while the longer of the two is expressed at low levels in a number of somatic tissues. -
Cellular localization
Cytoplasmic -
Database links
- Entrez Gene: 84220 Human
- Omim: 612708 Human
- SwissProt: Q99666 Human
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Alternative names
- BS63 antibody
- Ran binding protein 2 like 1 antibody
- RANBP2 like and GRIP domain containing 5 antibody
see all
Images
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Immunofluorescence of RGPD5 in Human testis tissue with ab106360 at 20 ug/mL.
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Anti-RGPD5 antibody (ab106360) at 1 µg/ml + Human thymus tissue lysate at 15 µg
Predicted band size: 199 kDa -
ab106360 at 10 µg/ml staining RGPD5 in Human testis tissue by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab106360 has not yet been referenced specifically in any publications.