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Rabbit polyclonal to RGS1
Predicted to work with:
Recombinant fragment, corresponding to a region within amino acids 1-209 of Human RGS1 (UniProt Q08116).
K562 cell lysate; Human Cal27 xenograft tissue.
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 79% PBS, 20% Glycerol
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 24 kDa.
1/100 - 1/1000.
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. This protein may be involved in the regulation of B-cell activation and proliferation.
B-cell specific. Expression is relatively low in B-cells and chronic lymphocytic leukemia B-cells; however, in other types of malignant B-cell such as non-Hodgkin lymphoma and hairy cell leukemia, expression is constitutively high.
Contains 1 RGS domain.
Could be phosphorylated. Might be functionally regulated by protein kinase(s).
Information by UniProt
B cell activation protein BL34 antibody
B-cell activation protein BL34 antibody
Western blot - Anti-RGS1 antibody (ab154973)
Anti-RGS1 antibody (ab154973) at 1/1000 dilution + K562 whole cell lysate at 30 µg
Predicted band size: 24 kDa 12% SDS PAGE
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RGS1 antibody (ab154973)
Immunohistochemical analysis of paraffin-embedded Human Cal27 xenograft tissue labeling RGS1 with ab154973 at 1/500 dilution.
has not yet been referenced specifically in any publications.
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