Overview

  • Product name

  • Description

    Rabbit polyclonal to RGS19
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Rhesus monkey
  • Immunogen

    Recombinant fragment within Human RGS19. The exact sequence is proprietary.
    Database link: P49795

  • Positive control

    • WB: RGS19-transfected HEK-293T whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab229253 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/5000 - 1/20000. Predicted molecular weight: 25 kDa.

Target

  • Function

    Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
  • Tissue specificity

    Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.
  • Sequence similarities

    Contains 1 RGS domain.
  • Post-translational
    modifications

    Fatty acylated. Heavily palmitoylated in the cysteine string motif.
    Phosphorylated, mainly on serine residues.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • G alpha interacting protein antibody
    • G protein signalling regulator 19 antibody
    • G protein, alpha-interacting protein antibody
    • G-alpha-interacting protein antibody
    • GAIP antibody
    • GNAI3IP antibody
    • Guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein antibody
    • Regulator of G protein signalling 19 antibody
    • Regulator of G-protein signaling 19 antibody
    • RGS19 antibody
    • RGS19_HUMAN antibody
    • RGSGAIP antibody
    see all

Images

  • All lanes : Anti-RGS19 antibody (ab229253) at 1/10000 dilution

    Lane 1 : HEK-293T whole cell lysate
    Lane 2 : RGS19-transfected HEK-293T whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 25 kDa



    12% SDS-PAGE

References

ab229253 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab229253.
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