Key features and details
- Rabbit polyclonal to RGS19
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-RGS19 antibody
See all RGS19 primary antibodies
DescriptionRabbit polyclonal to RGS19
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Rhesus monkey
Recombinant fragment within Human RGS19. The exact sequence is proprietary.
Database link: P49795
- WB: RGS19-transfected HEK-293T whole cell lysate.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.025% Proclin 300
Constituents: PBS, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab229253 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/5000 - 1/20000. Predicted molecular weight: 25 kDa.|
FunctionInhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
Tissue specificityHighest expression in lung. Placenta, liver and heart also express high levels of GAIP.
Sequence similaritiesContains 1 RGS domain.
modificationsFatty acylated. Heavily palmitoylated in the cysteine string motif.
Phosphorylated, mainly on serine residues.
- Information by UniProt
- G alpha interacting protein antibody
- G protein signalling regulator 19 antibody
- G protein, alpha-interacting protein antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab229253 has not yet been referenced specifically in any publications.