Product nameAnti-RGS19 antibody - C-terminal
See all RGS19 primary antibodies
DescriptionRabbit polyclonal to RGS19 - C-terminal
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Rhesus monkey
Synthetic peptide within Human RGS19 (C terminal). The exact sequence is proprietary. Conjugated to a protein carrier.
Database link: P49795
- WB: RGS19-transfected HEK-293T cell lysate.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: PBS, 10% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab228611 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 25 kDa.|
FunctionInhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
Tissue specificityHighest expression in lung. Placenta, liver and heart also express high levels of GAIP.
Sequence similaritiesContains 1 RGS domain.
modificationsFatty acylated. Heavily palmitoylated in the cysteine string motif.
Phosphorylated, mainly on serine residues.
- Information by UniProt
- G alpha interacting protein antibody
- G protein signalling regulator 19 antibody
- G protein, alpha-interacting protein antibody
All lanes : Anti-RGS19 antibody - C-terminal (ab228611) at 1/500 dilution
Lane 1 : Non-transfected HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) cell lysate
Lane 2 : RGS19-transfected HEK-293T cell lysate
Developed using the ECL technique.
Predicted band size: 25 kDa
ab228611 has not yet been referenced specifically in any publications.