Key features and details
- Rabbit polyclonal to RGS3 - C-terminal
- Suitable for: WB, IHC-P
- Reacts with: Rat, Human
- Isotype: IgG
Product nameAnti-RGS3 antibody - C-terminal
See all RGS3 primary antibodies
DescriptionRabbit polyclonal to RGS3 - C-terminal
SpecificityNo cross reactivity with other proteins.
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Rat, Human
Predicted to work with: Mouse
- Rat testis, rat brain rat spleen, HeLa and U87 cell lysates; rat intestine tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab191047 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 106 kDa.|
|IHC-P||Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionDown-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.
Sequence similaritiesContains 1 C2 domain.
Contains 1 PDZ (DHR) domain.
Contains 1 RGS domain.
modificationsPhosphorylated by cyclic GMP-dependent protein kinase.
Cellular localizationCytoplasm. Nucleus. Cell membrane. Long isoforms are cytoplasmic and associated with the plasma membrane. Short isoforms are nuclear.
- Information by UniProt
- C2PA antibody
- FLJ20370 antibody
- FLJ31516 antibody
Immunohistochemical analysis of paraffin-embedded rat intestine tissue labeling RGS3 with ab191047 at 1 µg/ml.
All lanes : Anti-RGS3 antibody - C-terminal (ab191047) at 0.5 µg/ml
Lane 1 : Rat testis tissue lysate
Lane 2 : Rat brain tissue lysate
Lane 3 : Rat spleen tissue lysate
Lane 4 : HeLa cell lysate
Lane 5 : U87 cell lysate
Predicted band size: 106 kDa
ab191047 has not yet been referenced specifically in any publications.