- Datasheet
- Specific References
- Protocols
Overview
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Product nameAnti-RGS8 antibody
See all RGS8 primary antibodies -
DescriptionChicken polyclonal to RGS8
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Host speciesChicken
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Tested applicationsSuitable for: WBmore details
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Species reactivityReacts with: Mouse, Rat, Human
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Immunogen
Synthetic peptide:
MAALLMPRRN KGMRTRLGCL SHKSDSCSDF TAILPDKPNR ALKRLSTEEA TRWADSFDVL LSHKYGVAAF RAFLKTEFSE ENLEF
, corresponding to amino acids 1-85 of Human RGS8. -
General notes
Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein coupled receptor complexes. RGS proteins are GTPase activating proteins for Gi and Gq class G alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination. RGS8 is a brain specific RGS protein.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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Storage bufferConstituent: PBS
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Concentration information loading... -
PurityImmunogen affinity purified
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Primary antibody notesRegulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein coupled receptor complexes. RGS proteins are GTPase activating proteins for Gi and Gq class G alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination. RGS8 is a brain specific RGS protein.
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ClonalityPolyclonal
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IsotypeIgY
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Research areas
Applications
Our Abpromise guarantee covers the use of ab14267 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/2000. Predicted molecular weight: 21 kDa. |
Target
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FunctionInhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Preferentially binds to G(o)-alpha and G(i)-alpha-3.
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Sequence similaritiesContains 1 RGS domain.
- Information by UniProt
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Database links
- Entrez Gene: 85397 Human
- Entrez Gene: 67792 Mouse
- Entrez Gene: 54297 Rat
- Omim: 607189 Human
- SwissProt: P57771 Human
- SwissProt: Q8BXT1 Mouse
- SwissProt: P49804 Rat
- Unigene: 20982 Human
see all -
Alternative names
- Regulator of G Protein Signalling 8 antibody
- Regulator of G-protein signaling 8 antibody
- RGS8 antibody
- RGS8_HUMAN antibody
Images
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Western blot - Anti-RGS8 antibody (ab14267)E coli-derived fusion protein as test antigen (amino acids 1-85 of human RGS8 + 52kDa in-frame fusion partner). Affinity-Purified IgY dilution: 1/2000, Goat anti-IgY-HRP dilution: 1/1000. Colorimetric method for signal development.
E coli-derived fusion protein as test antigen (amino acids 1-85 of human RGS8 + 52kDa in-frame fusion partner). Affinity-Purified IgY dilution: 1/2000, Goat anti-IgY-HRP dilution: 1/1000. Colorimetric method for signal development.
Protocols
References
ab14267 has not yet been referenced specifically in any publications.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"