Overview

  • Product name

    RHC-80267, diacylglycerol lipase inhibitor
  • Description

    Selective diacylglycerol lipase inhibitor
  • Biological description

    Selective diacylglycerol lipase inhibitor (IC50 = 4 μM). Enhances acetylcholine induced smooth muscle relaxation in vitro.
  • Purity

    > 98%
  • CAS Number

    83654-05-1
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Ghisdal P  et al. The diacylglycerol lipase inhibitor RHC-80267 potentiates the relaxation to acetylcholine in rat mesenteric artery by anti-cholinesterase action. Eur J Pharmacol 517:97-102 (2005). Read more (PubMed: 15958263) »
  • Suzuki H  et al. Effects of RHC-80267, an inhibitor of diacylglycerol lipase, on excitation of circular smooth muscle of the guinea-pig gastric antrum. J Smooth Muscle Res 38:153-64 (2002). Read more (PubMed: 12713022) »
  • Sutherland CA & Amin D Relative activities of rat and dog platelet phospholipase A2 and diglyceride lipase. Selective inhibition of diglyceride lipase by RHC 80267. J Biol Chem 257:14006-10 (1982). Read more (PubMed: 7142192) »

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