Key features and details
- Mouse monoclonal  to RHCE
- Suitable for: IHC-P, IHC-Fr, Agglutination, WB, IP, ELISA, Flow Cyt
- Reacts with: Human
- Isotype: IgM
Product nameAnti-RHCE antibody 
DescriptionMouse monoclonal  to RHCE
SpecificityRecognizes human Rho(C) antigen of the Rhesus system system of blood typing. Anti-RhoC variants reactivity: R1R2, R1RZ, R1wR1w, R1wr, rwr, Cw, R1wR1x, Cx, rsr. Does not crossreact with other Rhesus antigens. The immunogen (RhoC) bears no relationship to the RhoC-GTPase which is an oncogenic protein (RHOC). The clone number has been updated from (1V008) to (109) both clone numbers name the same antibody clone.
Tested applicationsSuitable for: IHC-P, IHC-Fr, Agglutination, WB, IP, ELISA, Flow Cytmore details
Species reactivityReacts with: Human
Peripheral blood lymphocytes from hyperimmune anti-C donor transformed by Epstein-Barr virus.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.1% Sodium azide
Constituents: 1.74% Sodium chloride, 0.0365% EDTA, 40% Glycerol
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab80716 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA: Use at an assay dependent dilution.
Flow Cyt: Use at an assay dependent dilution.
IHC-P: Use at an assay dependent dilution. Antigen retrieval is recommended.
IHC-Fr: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 22 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceThe Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease. There are thirteen named isoforms.
Cellular localizationMembrane; Multi-pass membrane protein.
- Blood group RhCcEe antigen antibody
- CD240CE antibody
- CD240CE antigen antibody
ab80716 has not yet been referenced specifically in any publications.