Overview

  • Product name

    Rhodadyntrade C10, cell-permeable dynamin I inhibitor
  • Description

    Highly potent cell-permeable dynamin I inhibitor
  • Biological description

    Highly potent cell-permeable dynamin I GTPase activity inhibitor (IC50 values are 7.1 and 30.3 μM at dynamin I and dynamin II, respectively). Blocks clathrin-mediated endocytosis of transferrin when applied for 30 minutes to U2OS cells in culture (IC50 = 7.0 μM).
    Rhodadyn™ B10 negative control also available (ab120796).

    Robertson J et al. The rhodadyn™ a new class of small molecule inhibitors of dynamin GTPase. ACS Med. Chem (2012).
  • Purity

    > 98%
  • General notes

    Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovations Ltd. Rhodadyn™ is a trademark of Children's Medical Research Institute and Newcastle Innovation Ltd.
  • Chemical structure

    Chemical Structure

Properties

References

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