Overview

  • Product name
    Anti-Rhodopsin antibody [EPR7996]
    See all Rhodopsin primary antibodies
  • Description
    Rabbit monoclonal [EPR7996] to Rhodopsin
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
    Unsuitable for: ICC or IP
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Synthetic peptide within Human Rhodopsin aa 300-400. The exact sequence is proprietary.

  • Positive control
    • Rat eyeball lysate; Human retina tissue.
  • General notes

    Mouse: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab155097 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 39 kDa.
IHC-P 1/50 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
  • Application notes
    Is unsuitable for ICC or IP.
  • Target

    • Function
      Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal.
    • Tissue specificity
      Rod shaped photoreceptor cells which mediates vision in dim light.
    • Involvement in disease
      Retinitis pigmentosa 4
      Night blindness, congenital stationary, autosomal dominant 1
    • Sequence similarities
      Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
    • Post-translational
      modifications
      Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
      Contains one covalently linked retinal chromophore.
    • Cellular localization
      Membrane. Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) photosensory cilia.
    • Information by UniProt
    • Database links
    • Alternative names
      • CSNBAD1 antibody
      • MGC138309 antibody
      • MGC138311 antibody
      • OPN 2 antibody
      • OPN2 antibody
      • opsd antibody
      • OPSD_HUMAN antibody
      • opsin 2 antibody
      • Opsin 2 rod pigment antibody
      • Opsin-2 antibody
      • Opsin2 antibody
      • Retinitis Pigmentosa 4 antibody
      • Retinitis pigmentosa 4 autosomal dominant antibody
      • RHO antibody
      • Rhodopsin antibody
      • RP 4 antibody
      • RP4 antibody
      see all

    Images

    • Anti-Rhodopsin antibody [EPR7996] (ab155097) at 1/1000 dilution + Rat eyeball lysate at 10 µg

      Secondary
      Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size: 39 kDa

    • Immunohistochemical analysis of paraffin-embedded Human retina tissue labeling Rhodopsin with ab155097 at 1/50 dilution.
    • Immunohistochemical analysis of paraffin embedded Human ovarian carcinoma tissue using ab155097 showing -ve staining.

    • Immunohistochemical analysis of paraffin embedded Human normal pancreas tissue using ab155097 showing -ve staining.

    • Immunohistochemical analysis of paraffin embedded Human hepatocellular carcinoma tissue using ab155097 showing -ve staining.

    • Immunohistochemical analysis of paraffin embedded Human normal colon tissue using ab155097 showing -ve staining.

    References

    ab155097 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab155097.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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