WB, IHC-Pmore details Unsuitable for:
ICC or IP
Synthetic peptide within Human Rhodopsin aa 300-400. The exact sequence is proprietary.
Rat eyeball lysate; Human retina tissue.
Mouse: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents
We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.
This product is a recombinant rabbit monoclonal antibody.
1/50 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
Is unsuitable for ICC or IP.
Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal.
Rod shaped photoreceptor cells which mediates vision in dim light.
Involvement in disease
Retinitis pigmentosa 4 Night blindness, congenital stationary, autosomal dominant 1
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region. Contains one covalently linked retinal chromophore.
Membrane. Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) photosensory cilia.