Overview

  • Product name

    Anti-Rhodopsin antibody - N-terminal
    See all Rhodopsin primary antibodies
  • Description

    Rabbit polyclonal to Rhodopsin - N-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Fr, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rabbit, Guinea pig, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide within Human Rhodopsin (N terminal). The exact sequence is proprietary. (Carrier-protein conjugated).
    Database link: P08100

  • Positive control

    • WB: APRE19 whole cell extract; Mouse eye extract. IHC-Fr: Mouse retina tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab229650 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/100 - 1/1000.
WB 1/500 - 1/3000. Predicted molecular weight: 39 kDa.

Target

  • Function

    Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal.
  • Tissue specificity

    Rod shaped photoreceptor cells which mediates vision in dim light.
  • Involvement in disease

    Retinitis pigmentosa 4
    Night blindness, congenital stationary, autosomal dominant 1
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
  • Post-translational
    modifications

    Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
    Contains one covalently linked retinal chromophore.
  • Cellular localization

    Membrane. Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) photosensory cilia.
  • Information by UniProt
  • Database links

  • Alternative names

    • CSNBAD1 antibody
    • MGC138309 antibody
    • MGC138311 antibody
    • OPN 2 antibody
    • OPN2 antibody
    • opsd antibody
    • OPSD_HUMAN antibody
    • opsin 2 antibody
    • Opsin 2 rod pigment antibody
    • Opsin-2 antibody
    • Opsin2 antibody
    • Retinitis Pigmentosa 4 antibody
    • Retinitis pigmentosa 4 autosomal dominant antibody
    • RHO antibody
    • Rhodopsin antibody
    • RP 4 antibody
    • RP4 antibody
    see all

Images

  • Anti-Rhodopsin antibody - N-terminal (ab229650) at 1/1000 dilution + Mouse eye extract at 50 µg

    Secondary
    HRP-conjugated anti-rabbit IgG

    Predicted band size: 39 kDa



    10% SDS-PAGE gel.

  • Frozen adult mouse retina tissue stained for Rhodopsin (green) using ab229650 at 1/250 dilution in immunohistochemical analysis.

    Red: beta Tubulin 3, stained by beta Tubulin 3 antibody at 1/250 dilution.
    Blue: DAPI.

  • Anti-Rhodopsin antibody - N-terminal (ab229650) at 1/1000 dilution + ARPE19 whole cell extract at 30 µg

    Predicted band size: 39 kDa



    10% SDS-PAGE gel.

References

ab229650 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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