Overview

  • Product name
    Anti-RhoGDI antibody
    See all RhoGDI primary antibodies
  • Description
    Rabbit polyclonal to RhoGDI
  • Host species
    Rabbit
  • Specificity
    ab52850 is specific for the RhoGDI alpha protein and does not cross react with the related RhoGDI beta or RhoGDI gamma proteins.
  • Tested applications
    Suitable for: IP, WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Cow
  • Immunogen

    Synthetic peptide corresponding to 25 amino acids derived from the N terminal of Human RhoGDI.

  • Positive control
    • HeLa and NIH 3T3 lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab53850 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use a concentration of 5 - 10 µg/ml.
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 23 kDa.
ELISA Use a concentration of 0.1 - 1 µg/ml.

Target

  • Function
    Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
  • Sequence similarities
    Belongs to the Rho GDI family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
    see all
  • Alternative names
    • ARHGDIA antibody
    • fa96g11 antibody
    • GDIA 1 antibody
    • GDIA1 antibody
    • GDIR1_HUMAN antibody
    • MGC117248 antibody
    • NPHS8 antibody
    • Rho GDI 1 antibody
    • Rho GDI alpha antibody
    • Rho GDI antibody
    • Rho GDP dissociation inhibitor (GDI) alpha antibody
    • Rho GDP dissociation inhibitor 1 antibody
    • Rho GDP dissociation inhibitor alpha antibody
    • Rho GDP-dissociation inhibitor 1 antibody
    • Rho-GDI alpha antibody
    • RhoGDI 1 antibody
    • RhoGDI alpha antibody
    • RHOGDI antibody
    • RhoGDI1 antibody
    • wu:fa96g11 antibody
    • zgc:55554 antibody
    • zgc:77681 antibody
    see all

References

This product has been referenced in:
  • Moretti AIS  et al. Conserved Gene Microsynteny Unveils Functional Interaction Between Protein Disulfide Isomerase and Rho Guanine-Dissociation Inhibitor Families. Sci Rep 7:17262 (2017). WB, IP, ICC/IF ; Mouse . Read more (PubMed: 29222525) »
  • Pescatore LA  et al. Protein Disulfide Isomerase Is Required for Platelet-derived Growth Factor-induced Vascular Smooth Muscle Cell Migration, Nox1 NADPH Oxidase Expression, and RhoGTPase Activation. J Biol Chem 287:29290-300 (2012). ICC/IF, WB ; Rabbit . Read more (PubMed: 22773830) »

See all 2 Publications for this product

Publishing research using ab53850? Please let us know so that we can cite the reference in this datasheet.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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