Product nameAnti-Ricin toxin A chain antibody
See all Ricin toxin A chain primary antibodies
DescriptionRabbit polyclonal to Ricin toxin A chain
Tested applicationsSuitable for: Electron Microscopy, ELISA, WBmore details
Species reactivityReacts with: Other species
Full length native protein: Purified intact A chain from RCA 60.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.097% Sodium azide
Constituents: 0.0268% PBS, 2.9% Sodium chloride
Purification notessterile-filtered (0.22 mm pore size) serum with the addition of 15 mM NaN3
Our Abpromise guarantee covers the use of ab27169 in the following tested applications.
|Electron Microscopy||Use at an assay dependent concentration. PubMed: 21886775|
|WB||1/2000. Predicted molecular weight: 32 kDa.|
RelevanceRicin chain A (RTA) is a ribosome inactivating enzyme with a molecular weight of 32 kDa. RTA is normally linked by a disulfide bond to the galactose/N acetylgalactosamine binding lectin (34 kDa), also called the B chain or RTB. Together with RTB, RTA constitutes the heterodimeric cytotoxin Ricin (RCA 60) from Ricinus communis. This ricin, which is a type 2 RIP (ribosome inactivating protein) is among the most potent cytotoxins in nature. Ricin is highly toxic to animal cells and to a lesser extent to plant cells.
- Ricin A chain antibody
- Ricin antibody
This product has been referenced in:
- Marszalowicz GP et al. GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer. Oncotarget 5:9460-71 (2014). Read more (PubMed: 25294806) »
- Wang W et al. Mannosidase 2, alpha 1 Deficiency Is Associated with Ricin Resistance in Embryonic Stem (ES) Cells. PLoS One 6:e22993 (2011). Electron Microscopy . Read more (PubMed: 21886775) »