Product nameAnti-Ricin toxin A chain antibody
DescriptionRabbit polyclonal to Ricin toxin A chain
Tested applicationsSuitable for: Electron Microscopy, ELISA, WBmore details
Species reactivityReacts with Ricinus communis. Not yet tested in other species.
Full length native protein: Purified intact A chain from RCA 60.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.097% Sodium azide
Constituents: 0.0268% PBS, 2.9% Sodium chloride
Purification notessterile-filtered (0.22 mm pore size) serum with the addition of 15 mM NaN3
Our Abpromise guarantee covers the use of ab27169 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Electron Microscopy||Use at an assay dependent concentration. PubMed: 21886775|
|WB||1/2000. Predicted molecular weight: 32 kDa.|
RelevanceRicin chain A (RTA) is a ribosome inactivating enzyme with a molecular weight of 32 kDa. RTA is normally linked by a disulfide bond to the galactose/N acetylgalactosamine binding lectin (34 kDa), also called the B chain or RTB. Together with RTB, RTA constitutes the heterodimeric cytotoxin Ricin (RCA 60) from Ricinus communis. This ricin, which is a type 2 RIP (ribosome inactivating protein) is among the most potent cytotoxins in nature. Ricin is highly toxic to animal cells and to a lesser extent to plant cells.
- Ricin A chain antibody
- Ricin antibody
This product has been referenced in:
- Marszalowicz GP et al. GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer. Oncotarget 5:9460-71 (2014). Read more (PubMed: 25294806) »
- Wang W et al. Mannosidase 2, alpha 1 Deficiency Is Associated with Ricin Resistance in Embryonic Stem (ES) Cells. PLoS One 6:e22993 (2011). Electron Microscopy . Read more (PubMed: 21886775) »