Key features and details
- Rabbit polyclonal to RILP
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-RILP antibody
See all RILP primary antibodies
DescriptionRabbit polyclonal to RILP
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
- WB: Human placenta and ovary tumor lysates.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.2
Preservative: 0.09% Sodium azide
Constituents: 2% Sucrose, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab128616 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 44 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.|
FunctionRab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes.
Tissue specificityUbiquitous. Strongly expressed in fetal heart, heart, stomach, spleen, adrenal gland, thyroid gland, salivary gland, fetal liver, liver and lung. Poorly expressed in brain.
Sequence similaritiesContains 1 RILP-like domain.
Cellular localizationEndomembrane system. Late endosome membrane. Lysosome membrane. Cytoplasmic vesicle > phagosome membrane. Associated with late endosomal, lysosomal and phagosomal membranes. The interaction with RAB7A is necessary for its recruitment to phagosomes.
- Information by UniProt
- FLJ31193 antibody
- PP10141 antibody
- Rab interacting lysosomal protein antibody
ab128616 has been referenced in 4 publications.
- Im EJ et al. Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A. Nat Commun 10:1387 (2019). PubMed: 30918259
- Datta G et al. HIV-1 gp120 Promotes Lysosomal Exocytosis in Human Schwann Cells. Front Cell Neurosci 13:329 (2019). PubMed: 31379513
- Mohapatra G et al. A SUMOylation-dependent switch of RAB7 governs intracellular life and pathogenesis of Salmonella Typhimurium. J Cell Sci 132:N/A (2019). PubMed: 30510112
- Modica G et al. Rab7 palmitoylation is required for efficient endosome-to-TGN trafficking. J Cell Sci 130:2579-2590 (2017). PubMed: 28600323