Key features and details
- Rabbit polyclonal to RIM2
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-RIM2 antibody
See all RIM2 primary antibodies
DescriptionRabbit polyclonal to RIM2
SpecificityRIM2 is known to exist in multiple isoforms; this antibody should recognize most of them. The antibody is predicted to have no cross reactivity to other RIM proteins.
Tested applicationsSuitable for: IHC-P, WBmore details
Unsuitable for: IHC-FoFr
Species reactivityReacts with: Mouse, Rat, Human
A 17 amino acid synthetic peptide near the center of human RIM2
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab69860 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 5 µg/ml.|
|WB||Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 85 kDa (predicted molecular weight: 160 kDa).|
FunctionRab effector involved in exocytosis. May act as scaffold protein.
Sequence similaritiesContains 2 C2 domains.
Contains 1 FYVE-type zinc finger.
Contains 1 PDZ (DHR) domain.
Contains 1 RabBD (Rab-binding) domain.
Cellular localizationCell membrane. Cell junction > synapse. Cell junction > synapse > presynaptic cell membrane.
- Information by UniProt
- KIAA0751 antibody
- Non small cell lung cancer RimL3a protein antibody
- Non small cell lung cancer RimL3c protein antibody
All lanes : Anti-RIM2 antibody (ab69860) at 1 µg/ml
Lane 1 : Rat brain tissue lysate
Lane 2 : Rat brain tissue lysate with blocking peptide
Lysates/proteins at 15 µg per lane.
Predicted band size: 160 kDa
Observed band size: 85 kDa why is the actual band size different from the predicted?
Note: There are seven named isoforms of this protein.
ab69860 at 5 µg/ml staining RIM2 in human prostate tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections).
ab69860 has been referenced in 1 publication.
- Park JH et al. Glucagon-like peptide-1 enhances glucokinase activity in pancreatic ß-cells through the association of Epac2 with Rim2 and Rab3A. Endocrinology 153:574-82 (2012). WB ; Human . PubMed: 22147008