Key features and details
- Rabbit polyclonal to RIN1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-RIN1 antibody
See all RIN1 primary antibodies
DescriptionRabbit polyclonal to RIN1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide derived from the C terminal of Human RIN1.
- COLO205 cell lysate.
Storage instructionsShipped at 4°C. Store at -20ºC.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride
PBS is without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab138097 was affinity-purified from rabbit antiserum by immunogenic peptide affinity-chromatography.
Our Abpromise guarantee covers the use of ab138097 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 84 kDa.|
RelevanceRIN1 is a Ras effector protein which can affect Ras signaling in a variety of ways. It enhances signaling from ABL1 and ABL2 whcih are involved in regulation of cytoskeletal remodeling. It may function as a guanine nucleotide exchange factor in activation of Rab5a. Rin1 also competes with RAF1 for binding of the activated form of Ras. It may play a role inhibiting the modulation of neuronal plasticity in formation of aversive memory, and has been implicated as a tumor supressor gene in breast cancer.
Cellular localizationCytoplasmic and Plasma membrane
- Ras and Rab interactor 1 antibody
- ras inhibitor 1 antibody
- ras inhibitor antibody
ab138097 has not yet been referenced specifically in any publications.