Overview

  • Product name

  • Description

    Rabbit polyclonal to RIN1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from the C terminal of Human RIN1.

  • Positive control

    • COLO205 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab138097 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 84 kDa.

Target

  • Relevance

    RIN1 is a Ras effector protein which can affect Ras signaling in a variety of ways. It enhances signaling from ABL1 and ABL2 whcih are involved in regulation of cytoskeletal remodeling. It may function as a guanine nucleotide exchange factor in activation of Rab5a. Rin1 also competes with RAF1 for binding of the activated form of Ras. It may play a role inhibiting the modulation of neuronal plasticity in formation of aversive memory, and has been implicated as a tumor supressor gene in breast cancer.
  • Cellular localization

    Cytoplasmic and Plasma membrane
  • Database links

  • Alternative names

    • Ras and Rab interactor 1 antibody
    • ras inhibitor 1 antibody
    • ras inhibitor antibody
    • Ras inhibitor JC99 antibody
    • ras inhibitor RIN1 antibody
    • Ras interaction/interference protein 1 antibody
    • RIN 1 antibody
    see all

Images

  • Anti-RIN1 antibody (ab138097) at 1/500 dilution + COLO205 cell lysate at 30 µg

    Predicted band size: 84 kDa

References

ab138097 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab138097.
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