Risedronate sodium, osteoclast-mediated bone resorption inhibitor (ab143001)

Overview

  • Product name

    Risedronate sodium, osteoclast-mediated bone resorption inhibitor
  • Description

    Osteoclast-mediated bone resorption inhibitor
  • Purity

    > 99%
  • CAS Number

    115436-72-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    Sodium hydroxy-(1-hydroxy-1-phosphono-2-pyridin-3-ylethyl)phosphinate
  • Molecular weight

    305.09
  • Molecular formula

    C7H10NNaO7P2
  • PubChem identifier

    4194514
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1(=CN=CC(=C1)CC(P(=O)(O)[O-])(O)P(=O)(O)O).[Na+]
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Jeong HM  et al. Risedronate increases osteoblastic differentiation and function through connexin43. Biochem Biophys Res Commun 432:152-6 (2013). Read more (PubMed: 23376077) »
  • Nam SH  et al. Topically administered Risedronate shows powerful anti-osteoporosis effect in ovariectomized mouse model. Bone 50:149-55 (2012). Read more (PubMed: 22036912) »
  • Wang G  et al. Low-dose risedronate sodium protects bone cells after abrupt oestrogen withdrawal. J Int Med Res 40:1761-74 (2012). Read more (PubMed: 23206458) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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