Key features and details
- Atypical antipsychotic. 5-HT2A / D2 antagonist.
- CAS Number: 106266-06-2
- Purity: > 99%
- Soluble in DMSO to 10 mM and in ethanol to 10 mM
- Form / State: Solid
- Source: Synthetic
Product nameRisperidone, 5-HT2A / D2 antagonist
DescriptionAtypical antipsychotic. 5-HT2A / D2 antagonist.
Atypical antipsychotic agent. Potent 5-HT2A antagonist (Ki = 0.4 nM). Also displays high affinity at D2 receptors (Ki = 3.13 nM).
Chemical name3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl] ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 10 mM and in ethanol to 10 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120393 has been referenced in 1 publication.
- Blessing WW et al. Clozapine, chlorpromazine and risperidone dose-dependently reduce emotional hyperthermia, a biological marker of salience. Psychopharmacology (Berl) 234:3259-3269 (2017). PubMed: 28812124