Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 50% Glycerol, 0.01% BSA
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab204110 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/100 - 1/1000. Predicted molecular weight: 189 kDa.|
|IHC-P||1/100 - 1/500.
When using a fluorescent probe the recommended dilution is 1/50-1/200.
FunctionS-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene.
Tissue specificityHighly expressed in retinoblastoma cell lines and in brain tumors. Also expressed in a number of other cell lines and in brain, heart, skeletal muscle, liver and spleen. Isoform 1 is expressed in testis at much higher level than isoform 3.
Sequence similaritiesContains 8 C2H2-type zinc fingers.
Contains 1 SET domain.
- Information by UniProt
- GATA-3-binding protein G3B antibody
- HUMHOXY1 antibody
- KMT8 antibody
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Rat liver tissue tissue labeling RIZ1 with ab204110 at 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Rat brain tissue labeling RIZ1 with ab204110 at 1/200 dilution. The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated, used at 1/200 dilution for 40 minutes at 37°C. DAPI was used to stain the cell nuclei.
ab204110 has not yet been referenced specifically in any publications.