Mouse, Human Predicted to work with:
Rabbit, Horse, Chicken, Cow, Pig, Chimpanzee, Macaque monkey, Gorilla, Orangutan
Synthetic peptide within Human RKIP aa 150 to the C-terminus (C terminal) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary. (Peptide available as ab136276)
This antibody gave a positive signal in Mouse Hippocampus, Human Brain and Human Spinal Cord tissue lysates, as well as the following whole cell lysates: HeLa; A549; HepG2; A431; HL60.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40 Preservative: 0.02% Sodium azide Constituent: PBS Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Detects a band of approximately 21 kDa (predicted molecular weight: 21 kDa).
Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor.
Belongs to the phosphatidylethanolamine-binding protein family.