Overview

  • Product name

    RKRARKE, PKG Inhibitor
  • Description

    Competitive protein kinase G (PKG) inhibitor
  • Biological description

    Competitive protein kinase G (PKG) inhibitor. Ki = 86 µM for PKG; Ki = 550 µM for PKA. Potential inhibitory activity in neuronal systems.
  • Purity

    > 99%
  • CAS Number

    82801-73-8
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    943.12
  • Molecular formula

    C38H74N18O10
  • Sequence

    RKRARKE
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Wolfertstetter S  et al. cGMP-Dependent Protein Kinase Inhibitors in Health and Disease. Pharmaceuticals (Basel) 6:269-86 (2013). Read more (PubMed: 24275951) »
  • Guo LW & Ruoho AE Inhibition of cGMP-dependent protein kinase by the regulatory subunit of photoreceptor cGMP phosphodiesterase. Neurosci Lett 401:252-5 (2006). Read more (PubMed: 16603314) »
  • Glass DB Differential responses of cyclic GMP-dependent and cyclic AMP-dependent protein kinases to synthetic peptide inhibitors. Biochem J 213:159-64 (1983). Read more (PubMed: 6615418) »

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