Anti-RN-tre antibody (ab127552)
Key features and details
- Rabbit polyclonal to RN-tre
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-RN-tre antibody
See all RN-tre primary antibodies -
Description
Rabbit polyclonal to RN-tre -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow -
Immunogen
Recombinant fragment corresponding to Human RN-tre aa 1-164.
Database link: Q92738 -
Positive control
- 293T cell lysate, A431 and Jurkat whole cell lysates
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab127552 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 94 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 94 kDa. |
Target
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Function
Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex. -
Tissue specificity
Widely expressed. -
Sequence similarities
Contains 1 Rab-GAP TBC domain. -
Cellular localization
Golgi apparatus. Cytoplasmic vesicle. - Information by UniProt
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Database links
- Entrez Gene: 9712 Human
- Entrez Gene: 98910 Mouse
- Entrez Gene: 291309 Rat
- Omim: 605405 Human
- SwissProt: Q92738 Human
- SwissProt: Q80XC3 Mouse
- Unigene: 498661 Human
- Unigene: 688100 Human
see all -
Alternative names
- KIAA0019 antibody
- Related to the N terminus of tre antibody
- Related to the N-terminus of tre antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab127552 has not yet been referenced specifically in any publications.