Anti-RNA-dependent RNA polymerase (RDRP) antibody [R2] (ab180641)

Overview

  • Product name

    Anti-RNA-dependent RNA polymerase (RDRP) antibody [R2]
  • Description

    Mouse monoclonal [R2] to RNA-dependent RNA polymerase (RDRP)
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Species independent
  • Immunogen

    Tissue, cells or virus corresponding to RNA-dependent RNA polymerase (RDRP). of severe acute respiratory syndrome coronavirus (SARS-CoV).

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    ab180641 contains no additives.
  • Concentration information loading...
  • Purification notes

    ab180641 is in protein-free culture medium.
  • Clonality

    Monoclonal
  • Clone number

    R2
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab180641 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000.

Target

  • Relevance

    RdRP plays a role in the RNA interference (RNAi) pathway. RNAi is the process of sequence-specific,post-transcriptional gene silencing initiated by double-stranded RNA (dsRNA). Recent studies showed small interfering RNAs (siRNA) generated by Dicer from longer dsRNA specifically suppressed expression of genes in somatic and embryo cells. An RdRP activity might provide amplification by replication of long trigger dsRNAs or copying of short siRNAs in a primer-independent manner. The siRNA primed RdRP reaction converts target mRNA into dsRNA, as well as possibly replicating trigger dsRNA. Both products then serve as DICER substrates, initiating the RdRP chain reaction. RNAi is important for heterochromatin formation and accurate chromosome segregation.
  • Alternative names

    • Protein rdp 1 antibody
    • Protein rdp1 antibody
    • Rdp 1 antibody
    • Rdp1 antibody
    • Rdr 1 antibody
    • Rdr1 antibody
    • RdRP antibody
    • RNA dependent RNA polymerase homolog 1 antibody
    see all

References

ab180641 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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