Key features and details
- Mouse monoclonal [3C2] to RNase 7
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG1
Product nameAnti-RNase 7 antibody [3C2]
See all RNase 7 primary antibodies
DescriptionMouse monoclonal [3C2] to RNase 7
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Human
Full length native protein (purified) corresponding to Human RNase 7 aa 29-156. (Purified from cell culture supernatant).
Database link: Q9H1E1
- Human RNase 7 expressed by CHOEBNALT85 cell line.
Protein previously labeled as Ribonuclease 7.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.1% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab189222 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use at an assay dependent concentration.|
|WB||1/200 - 1/2000. Predicted molecular weight: 17 kDa.
1/500 to 1/2000 under non-reducing conditions; 1/200 to 1/1000 under reducing conditions.
FunctionExhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium.
Tissue specificityExpressed in various epithelial tissues including skin, respiratory tract, genito-urinary tract and, at a low level, in the gut. Expressed in liver, kidney, skeletal muscle and heart.
Sequence similaritiesBelongs to the pancreatic ribonuclease family.
- Information by UniProt
- EC 3.1.27.- antibody
- MGC133220 antibody
- Ribonuclease 7 antibody
Lane 1 : Anti-RNase 7 antibody [3C2] (ab189222) at 1/500 dilution
Lane 2 : Anti-RNase 7 antibody [3C2] (ab189222) at 1/200 dilution
All lanes : Human RNase 7 expressed by CHOEBNALT85 cell line (cell culture supernatant)
Lysates/proteins at 10 µl per lane.
Predicted band size: 17 kDa
Lane 1: Non-reduced conditions; Lane 2: Reduced conditions
ab189222 has not yet been referenced specifically in any publications.