Overview

  • Product name
    Anti-RNase 7 antibody
    See all RNase 7 primary antibodies
  • Description
    Rabbit polyclonal to RNase 7
  • Host species
    Rabbit
  • Specificity
    ab81470 reacts with a 17 kDa Ribonuclease 7 protein. It also cross reacts with Ribonuclease 8 protein.
  • Tested applications
    Suitable for: IHC-Fr, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human RNase 7 (N terminal).

  • General notes

    Protein previously labeled as Ribonuclease 7.

Properties

Applications

Our Abpromise guarantee covers the use of ab81470 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/200 - 1/1000.
WB 1/500 - 1/5000. Predicted molecular weight: 17 kDa.

Target

  • Function
    Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium.
  • Tissue specificity
    Expressed in various epithelial tissues including skin, respiratory tract, genito-urinary tract and, at a low level, in the gut. Expressed in liver, kidney, skeletal muscle and heart.
  • Sequence similarities
    Belongs to the pancreatic ribonuclease family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
    • Alternative names
      • EC 3.1.27.- antibody
      • MGC133220 antibody
      • Ribonuclease 7 antibody
      • ribonuclease, RNase A family, 7 antibody
      • RNAS7_HUMAN antibody
      • RNase 7 antibody
      • RNASE7 antibody
      • SAP 2 antibody
      • SAP-2 antibody
      • Skin derived antimicrobial protein 2 antibody
      • Skin-derived antimicrobial protein 2 antibody
      see all

    Images

    • Western blot - Anti-RNase 7 antibody (ab81470)
      Western blot - Anti-RNase 7 antibody (ab81470)
      All lanes : Anti-RNase 7 antibody (ab81470) at 1/500 dilution

      Lane 1 : Human small intestine tissue lysate - total protein (ab29276)
      Lane 2 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution

      Developed using the ECL technique.

      Predicted band size: 17 kDa
      Observed band size: 17 kDa
      Additional bands at: 37 kDa, 40 kDa. We are unsure as to the identity of these extra bands.


      Exposure time: 20 minutes

    References

    ab81470 has not yet been referenced specifically in any publications.

    Publishing research using ab81470? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

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    1 Review or Q&A

    10
    Votes: Highest First

    I'm interested in your anti-RNase 7 antibody (ab81470) as an ELISA
    antibody for research.
    Did you test it for ELISA? And if you did: How are the results, and if
    it hadn't been tested: Would you consider it sensible to use it for
    ELISA?

    Thank you very much for your interest in ab81470.

    To our knowledge, ab81470 has not been tested in ELISA. Therefore, I can offer a discount off a future purchase if you buy ab81470 now, test it in ELISA and submit feedback to us in the form ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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