Overview

  • Product name

    Anti-RNASE6 antibody
  • Description

    Rabbit polyclonal to RNASE6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 25-144 of Human RNASE6 (Q93091).

  • Positive control

    • Human Liver tissue

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab121111 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Use buffer at pH 6 for antigen retrieval.

Target

  • Function

    May have a role in host defense.
  • Tissue specificity

    Strong expression in lung, followed by heart, placenta, kidney, pancreas, liver, brain and skeletal muscle. Also expressed in monocytes and neutrophils.
  • Sequence similarities

    Belongs to the pancreatic ribonuclease family.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • Ribonuclease K6 antibody
    • RNAS6_HUMAN antibody
    • RNase K6 antibody
    • RNASE6 antibody

Images

  • Immunohistochemical staining of Human liver shows moderate cytoplasmic positivity in hepatocytes, ab121111 used at a dilution of 1/25.

References

This product has been referenced in:

  • Becknell B  et al. Ribonucleases 6 and 7 have antimicrobial function in the human and murine urinary tract. Kidney Int N/A:N/A (2014). Read more (PubMed: 25075772) »
See 1 Publication for this product

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