Key features and details
- Rabbit polyclonal to RNF126
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-RNF126 antibody
See all RNF126 primary antibodies
DescriptionRabbit polyclonal to RNF126
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
- Jurkat and K562 cell lysates; Human thyroid cancer tissue.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS
(without Mg2+ and Ca2+)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab183102 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/350 - 1/2000. Predicted molecular weight: 36 kDa.|
FunctionE3 ubiquitin-protein ligase. By ubiquitinating CDKN1A/p21 and targeting it for proteasomal degradation, may promote cell proliferation.
Tissue specificityHighly expressed in liver and testis.
Sequence similaritiesContains 1 RING-type zinc finger.
Cellular localizationCytoplasm. Nucleus.
- Information by UniProt
- E3 ubiquitin-protein ligase RNF126 antibody
- FLJ20552 antibody
- MGC1022 antibody
All lanes : Anti-RNF126 antibody (ab183102) at 1/350 dilution
Lane 1 : Jurkat cell lysate
Lane 2 : K562 cell lysate
Lysates/proteins at 40 µg per lane.
All lanes : Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
Predicted band size: 36 kDa
Exposure time: 20 seconds
Immunohistochemical analysis of paraffin embedded Human thyroid cancer tissue labeling RNF126 with ab183102 at 1/20 dilution. Image on the right is treated with the synthetic peptide.
ab183102 has been referenced in 1 publication.
- Yang X et al. RNF126 as a Biomarker of a Poor Prognosis in Invasive Breast Cancer and CHEK1 Inhibitor Efficacy in Breast Cancer Cells. Clin Cancer Res 24:1629-1643 (2018). PubMed: 29326282