Overview

  • Product name

    Anti-RNF167 antibody
  • Description

    Rabbit polyclonal to RNF167
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment corresponding to Human RNF167 aa 43-95.
    Sequence:

    ALFGATLSQEGLQGFLVEAHPDNACSPIAPPPPAPVNGSVFIALLRRFDC NFD


    Database link: Q9H6Y7

  • Positive control

    • Human testis tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab185099 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.
  • Tissue specificity

    Strongly expressed in the kidney and liver (at protein level).
  • Pathway

    Protein modification; protein ubiquitination.
  • Sequence similarities

    Contains 1 PA (protease associated) domain.
    Contains 1 RING-type zinc finger.
  • Post-translational
    modifications

    Auto-ubiquitinated in vitro in the presence of UBE2D1 and UBE2E1.
  • Cellular localization

    Endomembrane system. Targeted to cytoplasmic membranes.
  • Information by UniProt
  • Database links

  • Alternative names

    • 5730408C10Rik antibody
    • E3 ubiquitin-protein ligase RNF167 antibody
    • LP2254 antibody
    • RING finger protein 167 antibody
    • RING105 antibody
    • RN167_HUMAN antibody
    • RNF167 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human testis tissue labeling RNF167 at 1/200 dilution

References

ab185099 has not yet been referenced specifically in any publications.

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