Overview

  • Product name
  • Description
    Rabbit polyclonal to RNF216
  • Host species
    Rabbit
  • Specificity
    ab52564 detects TRIAD3.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Mouse RNF216.

  • Positive control
    • Mouse heart cytoplasmic cell lysate, testis and peripheral blood leukocytes.
  • General notes

    Protein previously labeled as TRIAD3.

Properties

Applications

Our Abpromise guarantee covers the use of ab52564 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 95 kDa (predicted molecular weight: 99 kDa).

Target

  • Relevance
    The TRIAD3 gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known.
  • Cellular localization
    Cytoplasmic
  • Database links
  • Alternative names
    • CAHH antibody
    • E3 ubiquitin ligase TRIAD3 antibody
    • E3 ubiquitin-protein ligase RNF216 antibody
    • ring finger protein 216 antibody
    • RNF216 antibody
    • Triad domain-containing protein 3 antibody
    • TRIAD3 antibody
    • U7I1 antibody
    • UBCE7IP1 antibody
    • Ubiquitin conjugating enzyme 7 interacting protein 1 antibody
    • UiP83 antibody
    • ZIN antibody
    • Zinc finger protein inhibiting NF kappa B antibody
    see all

Images

  • Lane 1 : Anti-RNF216 antibody (ab52564) at 0.5 µg/ml
    Lane 2 : Anti-RNF216 antibody (ab52564) at 1 µg/ml
    Lane 3 : Anti-RNF216 antibody (ab52564) at 2 µg/ml

    All lanes : Mouse heart cell lysate

    Predicted band size: 99 kDa
    Observed band size: 95 kDa
    why is the actual band size different from the predicted?

References

ab52564 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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