Overview

  • Product name

    Anti-RNF23 antibody
  • Description

    Rabbit polyclonal to RNF23
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
    Predicted to work with: Pig, Chimpanzee
  • Immunogen

    Recombinant fragment within Human RNF23 (internal sequence). The exact sequence is proprietary.
    Database link: Q9HCM9

  • Positive control

    • WB: A431 whole cell lysate; Mouse and rat testis lysates. IHC-P: Human colon carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab227542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 60 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function

    May facilitate apoptosis by inhibiting the poly-ubiquitination and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1.
  • Tissue specificity

    Ubiquitous; highly expressed in brain, heart, kidney, liver, skeletal muscle, spleen and testis.
  • Sequence similarities

    Belongs to the TRIM/RBCC family.
    Contains 1 B box-type zinc finger.
    Contains 1 B30.2/SPRY domain.
    Contains 1 RING-type zinc finger.
  • Cellular localization

    Cytoplasm > cytosol. Mitochondrion. Found predominantly in the cytosol. Partial shift from the cytosol to the mitochondria when co-localized with MOAP1.
  • Information by UniProt
  • Database links

  • Alternative names

    • HGNC:10065 antibody
    • MGC32984 antibody
    • RING finger protein 23 antibody
    • RNF23 antibody
    • Testis abundant finger protein antibody
    • Testis-abundant finger protein antibody
    • TFP antibody
    • TFP RING FINGER PROTEIN 23 antibody
    • TRI39_HUMAN antibody
    • Trim39 antibody
    • TRIM39B antibody
    • Tripartite motif containing 39 antibody
    • Tripartite motif-containing protein 39 antibody
    see all

Images

  • Anti-RNF23 antibody (ab227542) at 1/1000 dilution + A431 (human epidermoid carcinoma cell line) whole cell lysate at 30 µg

    Predicted band size: 60 kDa



    7.5% SDS-PAGE gel.

  • Anti-RNF23 antibody (ab227542) at 1/1000 dilution + Mouse testis lysate at 50 µg

    Predicted band size: 60 kDa



    7.5% SDS-PAGE gel.

  • Anti-RNF23 antibody (ab227542) at 1/1000 dilution + Rat testis lysate at 50 µg

    Predicted band size: 60 kDa



    7.5% SDS-PAGE gel.

  • Paraffin-embedded human colon carcinoma tissue stained for RNF23 using ab227542 at 1/500 dilution in immunohistochemical analysis.

References

ab227542 has not yet been referenced specifically in any publications.

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