Recombinant Anti-RNF36 antibody [EPR4755] (ab111943)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR4755] to RNF36
- Suitable for: WB
- Reacts with: Mouse, Human
Related conjugates and formulations
Overview
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Product name
Anti-RNF36 antibody [EPR4755]
See all RNF36 primary antibodies -
Description
Rabbit monoclonal [EPR4755] to RNF36 -
Host species
Rabbit -
Specificity
ab111943 detects at least 4 isoforms. -
Tested applications
Suitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- Human testis and Neuro-2a cell lysates.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR4755 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab111943 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/1000 - 1/10000. Detects a band of approximately 29-54 kDa (predicted molecular weight: 57 kDa).
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Notes |
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WB
1/1000 - 1/10000. Detects a band of approximately 29-54 kDa (predicted molecular weight: 57 kDa). |
Target
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Function
May play a role in apoptosis. -
Sequence similarities
Belongs to the TRIM/RBCC family.
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger. -
Post-translational
modificationsPhosphorylated. Phosphorylation is necessary for nuclear localization. -
Cellular localization
Nucleus speckle. - Information by UniProt
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Database links
- Entrez Gene: 140691 Human
- Entrez Gene: 70928 Mouse
- Entrez Gene: 311373 Rat
- SwissProt: Q86WT6 Human
- SwissProt: Q80X56 Mouse
- SwissProt: Q5BK82 Rat
- Unigene: 489254 Human
- Unigene: 379188 Mouse
see all -
Alternative names
- E3 ubiquitin protein ligase TRIM69 antibody
- HSD34 antibody
- RFP like domain containing protein trimless antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab111943 has been referenced in 3 publications.
- Rong X et al. TRIM69 inhibits cataractogenesis by negatively regulating p53. Redox Biol 22:101157 (2019). PubMed: 30844644
- Rihn SJ et al. TRIM69 Inhibits Vesicular Stomatitis Indiana Virus. J Virol 93:N/A (2019). PubMed: 31375575
- Wang K et al. Interferon-stimulated TRIM69 interrupts dengue virus replication by ubiquitinating viral nonstructural protein 3. PLoS Pathog 14:e1007287 (2018). PubMed: 30142214