Key features and details
- NF-κB inhibitor. Anti-inflammatory agent.
- CAS Number: 62645-28-7
- Purity: > 95%
- Soluble in ethanol to 10 mM and in DMSO to 100mM
- Form / State: Solid
- Source: Synthetic
Product nameRo 106-9920, NF-kappaB inhibitor
DescriptionNF-κB inhibitor. Anti-inflammatory agent.
NF-κB inhibitor. Anti-inflammatory agent. Selectively inhibits LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 μM). Inhibits TNF-α, IL-1β and IL-6 production. Shows anti-inflammatory effects in vivo. Orally active.
Storage instructionsStore at -20°C (desiccating conditions).
Solubility overviewSoluble in ethanol to 10 mM and in DMSO to 100mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Vitamin D Receptor
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab144655 has not yet been referenced specifically in any publications.