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ab45171 has been referenced in 41 publications.

  • Roberto GM  et al. MiR-708-5p is inversely associated with EWS/FLI1 Ewing sarcoma but does not represent a prognostic predictor. Cancer Genet 230:21-27 (2019). PubMed: 30470587
  • Yang Z  et al. DLC2 operates as a tumor suppressor gene in breast cancer via the RhoGTPase pathway. Oncol Lett 17:2107-2116 (2019). PubMed: 30719106
  • Deng R  et al. lncRNA SNHG1 negatively regulates miRNA-101-3p to enhance the expression of ROCK1 and promote cell proliferation, migration and invasion in osteosarcoma. Int J Mol Med 43:1157-1166 (2019). PubMed: 30592267
  • Jiang C  et al. RhoA/ROCK/ARHGAP26 signaling in the eutopic and ectopic endometrium is involved in clinical characteristics of adenomyosis. J Int Med Res 46:5019-5029 (2018). PubMed: 30387365
  • Vieira GM  et al. Prognostic value and functional role of ROCK2 in pediatric Ewing sarcoma. Oncol Lett 15:2296-2304 (2018). PubMed: 29434937
  • Sun XQ  et al. Total flavones of Rhododendron simsii Planch flower protect isolated rat heart from ischaemia-reperfusion injury and its mechanism of UTR-RhoA-ROCK pathway inhibition. J Pharm Pharmacol 70:1713-1722 (2018). PubMed: 30251312
  • Wang Y  et al. Adipokine RBP4 drives ovarian cancer cell migration. J Ovarian Res 11:29 (2018). PubMed: 29642915
  • Wang X  et al. Efficacy of extracts of Celastrus orbiculatus in suppressing migration and invasion by inhibiting the EZH2/ROCK1 signaling pathway in human nasopharyngeal carcinoma. Oncol Lett 15:6695-6700 (2018). PubMed: 29725411
  • Huang X  et al. Rho/Rho-associated protein kinase signaling pathway-mediated downregulation of runt-related transcription factor 2 expression promotes the differentiation of dental pulp stem cells into odontoblasts. Exp Ther Med 15:4457-4464 (2018). PubMed: 29731830
  • Cheng L  et al. Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity. Arch Toxicol 92:469-485 (2018). PubMed: 28871336
  • Zhang R  et al. Hirsutine induces mPTP-dependent apoptosis through ROCK1/PTEN/PI3K/GSK3ß pathway in human lung cancer cells. Cell Death Dis 9:598 (2018). PubMed: 29789524
  • Tang L  et al. RhoA/ROCK signaling regulates smooth muscle phenotypic modulation and vascular remodeling via the JNK pathway and vimentin cytoskeleton. Pharmacol Res 133:201-212 (2018). PubMed: 29791873
  • Katare R  et al. Progressive Decrease in Coronary Vascular Function Associated With Type 2 Diabetic Heart Disease. Front Physiol 9:696 (2018). PubMed: 29928236
  • Zhai L  et al. Picroside II protects the blood-brain barrier by inhibiting the oxidative signaling pathway in cerebral ischemia-reperfusion injury. PLoS One 12:e0174414 (2017). WB ; Rat . PubMed: 28388666
  • Wang X  et al. Clinicopathological significance of ROCK1 and PIK3CA expression in nasopharyngeal carcinoma. Exp Ther Med 13:1064-1068 (2017). WB, IHC-P ; Human . PubMed: 28450943
  • Majumder P  et al. Cellular levels of Grb2 and cytoskeleton stability are correlated in a neurodegenerative scenario. Dis Model Mech 10:655-669 (2017). PubMed: 28360125
  • Amaya CN  et al. Rho kinase proteins display aberrant upregulation in vascular tumors and contribute to vascular tumor growth. BMC Cancer 17:485 (2017). PubMed: 28709411
  • Kang H  et al. Vascular smooth muscle cell glycocalyx mediates shear stress-induced contractile responses via a Rho kinase (ROCK)-myosin light chain phosphatase (MLCP) pathway. Sci Rep 7:42092 (2017). PubMed: 28191820
  • Xu Q  et al. MicroRNA-1291 promotes endometrial fibrosis by regulating the ArhGAP29-RhoA/ROCK1 signaling pathway in a murine model. Mol Med Rep 16:4501-4510 (2017). PubMed: 28849001
  • Han J  et al. Involvement of Histamine and RhoA/ROCK in Penicillin Immediate Hypersensitivity Reactions. Sci Rep 6:33192 (2016). WB ; Mouse . PubMed: 27619816
  • Yanardag Açik D  et al. Investigation of Rho-Kinase Expressions and Polymorphisms in Mantle Cell Lymphoma Patients. Turk J Haematol 33:141-7 (2016). PubMed: 26377148
  • Henderson BW  et al. Rho-associated protein kinase 1 (ROCK1) is increased in Alzheimer's disease and ROCK1 depletion reduces amyloid-ß levels in brain. J Neurochem 138:525-31 (2016). PubMed: 27246255
  • Gentry EG  et al. Rho Kinase Inhibition as a Therapeutic for Progressive Supranuclear Palsy and Corticobasal Degeneration. J Neurosci 36:1316-23 (2016). PubMed: 26818518
  • Zhang GM  et al. MicroRNA-126 inhibits tumor cell invasion and metastasis by downregulating ROCK1 in renal cell carcinoma. Mol Med Rep 13:5029-2036 (2016). WB ; Human . PubMed: 27108693
  • Li G  et al. Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis. Oncotarget 6:1834-49 (2015). PubMed: 25595902
  • Zhu KC  et al. Afzelin exhibits anti-cancer activity against androgen-sensitive LNCaP and androgen-independent PC-3 prostate cancer cells through the inhibition of LIM domain kinase 1. Oncol Lett 10:2359-2365 (2015). WB ; Human . PubMed: 26622852
  • Luo J  et al. FSP-1 Impairs the Function of Endothelium Leading to Failure of Arteriovenous Grafts in Diabetic Mice. Endocrinology 156:2200-10 (2015). Mouse . PubMed: 25774552
  • Cai SD  et al. MicroRNA-144 inhibits migration and proliferation in rectal cancer by downregulating ROCK-1. Mol Med Rep 12:7396-402 (2015). PubMed: 26458302
  • Ko AR  et al. Endothelin-1 induces LIMK2-mediated programmed necrotic neuronal death independent of NOS activity. Mol Brain 8:58 (2015). IHC-FoFr ; Rat . PubMed: 26438559
  • Akagi EM  et al. ROCK1 as a novel prognostic marker in vulvar cancer. BMC Cancer 14:822 (2014). IHC-P ; Human . PubMed: 25380619
  • Hu J  et al. FERM domain-containing protein FRMD5 regulates cell motility via binding to integrin ß5 subunit and ROCK1. FEBS Lett 588:4348-56 (2014). PubMed: 25448675
  • Shimizu T  et al. Crucial role of ROCK2 in vascular smooth muscle cells for hypoxia-induced pulmonary hypertension in mice. Arterioscler Thromb Vasc Biol 33:2780-91 (2013). IHC-P . PubMed: 24135024
  • Melo FR  et al. Serglycin Proteoglycan Promotes Apoptotic versus Necrotic Cell Death in Mast Cells. J Biol Chem 287:18142-52 (2012). WB ; Mouse . PubMed: 22493512
  • Ueno K  et al. Tumor suppressor microRNA-493 decreases cell motility and migration ability in human bladder cancer cells by downregulating RhoC and FZD4. Mol Cancer Ther 11:244-53 (2012). IP ; Human . PubMed: 22057916
  • Daley WP  et al. ROCK1-directed basement membrane positioning coordinates epithelial tissue polarity. Development 139:411-22 (2012). ICC/IF ; Mouse . PubMed: 22186730
  • Guo H  et al. Downregulation of p57 accelerates the growth and invasion of hepatocellular carcinoma. Carcinogenesis 32:1897-904 (2011). PubMed: 22002319
  • Ueno K  et al. Tumour suppressor microRNA-584 directly targets oncogene Rock-1 and decreases invasion ability in human clear cell renal cell carcinoma. Br J Cancer 104:308-15 (2011). IHC-P ; Human . PubMed: 21119662
  • Cloutier M  et al. ROCK2 is involved in accelerated fetal lung development induced by in vivo lung distension. Pediatr Pulmonol 45:966-76 (2010). WB ; Mouse . PubMed: 20648664
  • Minase T  et al. Potentiation of nerve growth factor-induced neurite outgrowth by the ROCK inhibitor Y-27632: a possible role of IP3 receptors. Eur J Pharmacol 648:67-73 (2010). ICC/IF ; Rat . PubMed: 20854802
  • Kim JY  et al. Shh and ROCK1 modulate the dynamic epithelial morphogenesis in circumvallate papilla development. Dev Biol 325:273-80 (2009). PubMed: 19014928
  • Sommer B  et al. Extraction of membrane cholesterol disrupts caveolae and impairs serotonergic (5-HT2A) and histaminergic (H1) responses in bovine airway smooth muscle: role of Rho-kinase. Can J Physiol Pharmacol 87:180-95 (2009). WB, IHC-Fr ; Cow . PubMed: 19295659

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