Overview

  • Product name

    Anti-ROR beta/RORB antibody
    See all ROR beta/RORB primary antibodies
  • Description

    Rabbit polyclonal to ROR beta/RORB
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Sheep, Rabbit, Horse, Chicken, Hamster, Cow, Dog, Monkey, Gorilla, Bat
  • Immunogen

    Synthetic peptide corresponding to Human ROR beta/RORB. The peptide corresponds to 20 amino acids, of the ligand-binding domain. (NP_008845.2)
    Database link: Q92753

  • Positive control

    • Recombinant Human ROR beta/RORB protein (ab114845) can be used as a positive control in WB. Human brain thalamus tissue.
  • General notes

     This product was previously labelled as ROR beta

     

Properties

Applications

Our Abpromise guarantee covers the use of ab188756 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter.
  • Sequence similarities

    Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • bA133M9.1 antibody
    • NR1F2 antibody
    • Nuclear receptor ROR-beta antibody
    • Nuclear receptor RZR beta antibody
    • Nuclear receptor RZR-beta antibody
    • Nuclear receptor subfamily 1 group F member 2 antibody
    • OTTHUMP00000021486 antibody
    • RAR related orphan receptor B antibody
    • RAR related orphan receptor beta antibody
    • Retinoic acid binding receptor beta antibody
    • Retinoid-related orphan receptor-beta antibody
    • ROR BETA antibody
    • Rorb antibody
    • RORB_HUMAN antibody
    • RZR BETA antibody
    • RZRB antibody
    see all

Images

  • Immunohistochemical analysis of Formalin-Fixed, Paraffin-Embedded Human brain thalamus tissue labeling ROR beta/RORB with ab88756 at 5 µg/ml.

References

This product has been referenced in:

  • Wang RX  et al. Melatonin downregulates nuclear receptor RZR/ROR? expression causing growth-inhibitory and anti-angiogenesis activity in human gastric cancer cells in vitro and in vivo. Oncol Lett 12:897-903 (2016). IHC ; Mouse . Read more (PubMed: 27446366) »
See 1 Publication for this product

Customer reviews and Q&As

Application
Immunohistochemistry (PFA perfusion fixed frozen sections)
Sample
Mouse Tissue sections (Brain)
Antigen retrieval step
Heat mediated - Buffer/Enzyme Used: 10mM Sodium Citrate
Permeabilization
Yes - 0.3% Triton X-100
Specification
Brain
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 3% · Temperature: 18°C
Fixative
Formaldehyde

Mr. Yasushi Nakagawa

Verified customer

Submitted Dec 18 2015

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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