Overview

  • Product name

    Anti-ROR1 antibody - C-terminal
    See all ROR1 primary antibodies
  • Description

    Rabbit polyclonal to ROR1 - C-terminal
  • Host species

    Rabbit
  • Specificity

    ab181883 does not cross react to any other cellular protein.
  • Tested applications

    Suitable for: WB, ELISAmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human, Monkey
  • Immunogen

    Synthetic peptide corresponding to Human ROR1 aa 900-918 (C terminal). Coupled to a carrier protein using hetero bifunctional cross linker.
    Sequence:

    TVFGNKSQKPYKIDSKQAS


    Database link: Q01973

  • General notes

    Stabilized at a concentration 0.55-0.75mg/ml.

Properties

Applications

Our Abpromise guarantee covers the use of ab181883 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Detects a band of approximately 113 kDa (predicted molecular weight: 104 kDa).
ELISA 1/500.

Target

  • Function

    Tyrosine-protein kinase receptor whose role is not yet clear.
  • Tissue specificity

    Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm.
  • Sequence similarities

    Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
    Contains 1 FZ (frizzled) domain.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 kringle domain.
    Contains 1 protein kinase domain.
  • Developmental stage

    Expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • dJ537F10.1 antibody
    • Inactive tyrosine protein kinase transmembrane receptor ROR1 antibody
    • MGC99659 antibody
    • Neurotrophic tyrosine kinase antibody
    • Neurotrophic tyrosine kinase receptor related 1 antibody
    • Neurotrophic tyrosine kinase, receptor related 1 antibody
    • NTRKR1 antibody
    • OTTHUMP00000010573 antibody
    • OTTHUMP00000010574 antibody
    • OTTMUSP00000008344 antibody
    • Receptor tyrosine kinase like orphan receptor 1 antibody
    • receptor-related 1 antibody
    • RGD1559469 antibody
    • ROR 1 antibody
    • ROR1 antibody
    • ROR1_HUMAN antibody
    • RP11 24J23.1 antibody
    • Tyrosine kinase like orphan receptor 1 antibody
    • Tyrosine protein kinase transmembrane receptor ROR1 antibody
    • Tyrosine-protein kinase transmembrane receptor ROR1 antibody
    see all

References

ab181883 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab181883.
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