Key features and details
- Cell-permeable, selective CDK inhibitor
- CAS Number: 186692-46-6
- Purity: > 99%
- Soluble in DMSO to 10 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Product nameRoscovitine, CDK inhibitor
DescriptionCell-permeable, selective CDK inhibitor
Cell-permeable, selective inhibitor of cyclin-dependent kinases (CDKs), displaying higher potency and selectivity compared to olomoucine (ab120938). p34cdc2 inhibitor (IC50 = 0.2 μM). Also inhibits p33cdk2 and p33cdk5. Anti-angiogenic.
Storage instructionsShipped at Room Temperature. Store at -20°C. Store under desiccating conditions.
Solubility overviewSoluble in DMSO to 10 mM and in ethanol to 25 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Energy Metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141847 has not yet been referenced specifically in any publications.