Overview

  • Product name

  • Description

    Chicken polyclonal to Rotavirus
  • Host species

    Chicken
  • Specificity

    Ab33639 is specific to Rotavirus. Neutralizing indices reported with each lot.
  • Tested applications

    Suitable for: ELISA, Neutralisingmore details
  • Species reactivity

    Reacts with: Other species
  • Immunogen

    Rotavirus.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    Constituent: Whole serum
  • Purity

    Whole antiserum
  • Purification notes

    Sterile filtered serum produced in SPF (Specific Pathogen Free) chicken embryos.
  • Clonality

    Polyclonal
  • Isotype

    IgY
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab33639 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
Neutralising Use at an assay dependent dilution.

Target

  • Relevance

    Rotaviruses, members of the family Reoviridae, are a major cause of diarrhoea in young mammals. Rotavirus infections also result in economic losses in agriculture due to diarrhoea in calf, pig, sheep, and poultry rearing. Diarrhoea (or scours) due to the rotavirus Nebraska Calf Diarrhea Virus can affect calves up to 30 days of age or older. Diarrhoea begins 2 to 3 days after exposure. Diagnosis is by history, lesions (ulcers on the tongue, lips, and mouth) and diagnostic laboratory tests. Mortality rates may be as high as 50 percent, depending on the secondary bacteria present. Human rotaviruses, the major aetiological agents of severe infantile diarrhoea worldwide, display surprisingly diverse and complex serotypic specificities. Rotaviruses are 70 nm, non enveloped viruses comprised of a triple layered protein capsid; Outer capsid proteins are VP4 and VP7, Inner capsid -VP6 and Core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection; therefore, multiple serotypes of rotavirus mean multiple opportunities for infection. The combination of animal reservoirs for the virus and rotavirus gene reassortment provides the potential for dramatic genetic shifts (similar to influenza virus) which could give rise to altered host ranges and viral virulence.
  • Database links

    • Alternative names

      • Major inner capsid protein VP6 antibody
      • NSP4 antibody
      • VP6 antibody

    References

    ab33639 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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