Overview

  • Product name

    Anti-Rotavirus antibody (FITC)
    See all Rotavirus primary antibodies
  • Description

    Goat polyclonal to Rotavirus (FITC)
  • Host species

    Goat
  • Conjugation

    FITC. Ex: 493nm, Em: 528nm
  • Tested applications

    Suitable for: ICC/IF, ELISAmore details
  • Species reactivity

    Reacts with: Other species
  • Immunogen

    Tissue/ cell preparation: Bovine rotavirus (whole virus).

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C.
  • Storage buffer

    Preservative: 0.1% Sodium Azide.
    Constituents: 1% BSA, PBS, pH 7.2.
  • Concentration information loading...
  • Purity

    Ion Exchange Chromatography
  • Purification notes

    Ammonium sulfate fractionation and ion-exchange chromatography.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab31435 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/250. Acetone fixed.
ELISA Use at an assay dependent dilution.

Target

  • Relevance

    Rotaviruses, members of the family Reoviridae, are a major cause of diarrhoea in young mammals. Rotavirus infections also result in economic losses in agriculture due to diarrhoea in calf, pig, sheep, and poultry rearing. Diarrhoea (or scours) due to the rotavirus Nebraska Calf Diarrhea Virus can affect calves up to 30 days of age or older. Diarrhoea begins 2 to 3 days after exposure. Diagnosis is by history, lesions (ulcers on the tongue, lips, and mouth) and diagnostic laboratory tests. Mortality rates may be as high as 50 percent, depending on the secondary bacteria present. Human rotaviruses, the major aetiological agents of severe infantile diarrhoea worldwide, display surprisingly diverse and complex serotypic specificities. Rotaviruses are 70 nm, non enveloped viruses comprised of a triple layered protein capsid; Outer capsid proteins are VP4 and VP7, Inner capsid -VP6 and Core -VP2. The immunity acquired from exposure to rotavirus appears to be type specific following initial infection; therefore, multiple serotypes of rotavirus mean multiple opportunities for infection. The combination of animal reservoirs for the virus and rotavirus gene reassortment provides the potential for dramatic genetic shifts (similar to influenza virus) which could give rise to altered host ranges and viral virulence.
  • Database links

    • Alternative names

      • Major inner capsid protein VP6 antibody
      • NSP4 antibody
      • VP6 antibody

    References

    This product has been referenced in:

    See 1 Publication for this product

    Customer reviews and Q&As

    Question
    Answer

    Thank you for contacting us.

    The immunogen for this antibody is Nebraska Calf Diarrhea Virus (whole virus).



    The antibody recognizes rotavirus and is specific for ICPs and late structural (virion) antigens. No further epitope information has been determined.

    I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

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